Anjana Ranjit Mohan, Pradeepa Rajendra, Deepa Mohan, Datta Manjula, Sudha Vasudevan, Unnikrishnan Ranjit, Nath Lalith M, Das Ashok Kumar, Madhu Sri Venkata, Rao Paturi Vishnupriya, Shukla Deepak Kumar, Kaur Tanvir, Ali Mohammed K, Mohan Viswanathan
Madras Diabetes Research Foundation, Dr. Mohan's Diabetes Specialities Centre, WHO Collaborating Centre for Noncommunicable Diseases Prevention and Control, IDF Centre of Education, Chennai, India.
J Diabetes Sci Technol. 2011 Jul 1;5(4):906-14. doi: 10.1177/193229681100500413.
Currently available estimates of diabetes prevalence in India are based on published data derived from very few studies. The Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) study is a community-based survey conceived with the aim of obtaining the prevalence rates of diabetes in India as a whole, covering all 28 states, the National Capital Territory of Delhi, and two of the union territories in the mainland of India, with a total sample size of 124,000 individuals.
A stratified multistage sampling design has been used. In all study subjects, a structured questionnaire was administered and anthropometric parameters and blood pressure were measured. Fasting capillary blood glucose was first determined using a glucose meter. An oral glucose load was then administered to all subjects except those with self-reported diabetes, and the 2 h post-load capillary blood glucose was estimated. In every fifth subject, a fasting venous sample was collected for measurement of lipids and creatinine, a resting 12-lead electrocardiogram was performed, and dietary assessment questionnaire was administered. In all diabetic subjects, an additional diabetes questionnaire was used and a fasting venous sample drawn for glycated hemoglobin.
All biological samples collected were analyzed in a central laboratory. All data collected were stored electronically. Quality control was achieved through multiple tiers of checks.
The ICMR-INDIAB study is the first of its kind attempting to provide accurate and comprehensive state- and national-level data on diabetes prevalence in India.
目前印度糖尿病患病率的现有估计是基于极少数研究得出的已发表数据。印度医学研究理事会 - 印度糖尿病（ICMR - INDIAB）研究是一项基于社区的调查，旨在获取整个印度的糖尿病患病率，涵盖所有28个邦、德里国家首都辖区以及印度大陆的两个联邦属地，总样本量为124,000人。
采用分层多阶段抽样设计。对所有研究对象发放结构化问卷，并测量人体测量参数和血压。首先使用血糖仪测定空腹毛细血管血糖。然后除了自我报告患有糖尿病的患者外，对所有受试者进行口服葡萄糖耐量试验，并估算服糖后2小时毛细血管血糖。每五名受试者中，采集一份空腹静脉血样用于检测血脂和肌酐，进行一次静息12导联心电图检查，并发放饮食评估问卷。对所有糖尿病患者，使用额外的糖尿病问卷，并采集一份空腹静脉血样用于检测糖化血红蛋白。
所有采集的生物样本均在中央实验室进行分析。所有收集的数据均以电子方式存储。通过多层检查实现了质量控制。
ICMR - INDIAB研究是同类研究中首个尝试提供印度糖尿病患病率准确且全面的邦级和国家级数据的研究。
