Department of Pediatrics, Faculty of Medicine, Kuwait University, Kuwait.
Saudi J Gastroenterol. 2011 Sep-Oct;17(5):323-7. doi: 10.4103/1319-3767.84487.
BACKGROUND/AIMS: Inflammatory bowel disease (IBD) was previously thought a rare disease among children in Kuwait since most diarrhea cases were attributed to infections. In the past few years we observed an increase in the number of patients presenting with IBD. In this study we aimed to determine the epidemiology of IBD among children in the State of Kuwait.
The charts of all children with IBD who were referred to the pediatric gastroenterology unit during the period February 1998 to January 2008 were retrospectively reviewed.
Out of a total of 130 children with IBD, 92 (71%) had Crohn's disease, 36 (28%) had ulcerative colitis and two (1%) had indeterminate colitis. The estimated annual incidence for IBD was 2.16/10 5 /year. The age range was nine months-15 years (median: 11 years). Fifty-three percent of all patients were females and 77% were Kuwaiti nationals. Positive family history was found in 23%. The commonest presenting symptoms were abdominal pain (87%) and diarrhea (82%). Failure to thrive was detected in 35% and short stature in 20% at presentation. The ileocolonic region was the most common presentation site affected in Crohn's patients and pancolitis was the commonest in ulcerative colitis.
Inflammatory bowel disease is not uncommon in our children. We found no differences regarding disease presentation and clinical features compared to the Western world.
背景/目的:在科威特,过去人们认为炎症性肠病(IBD)在儿童中较为罕见,因为大多数腹泻病例归因于感染。但在过去几年中,我们观察到患有 IBD 的患者数量有所增加。本研究旨在确定科威特儿童 IBD 的流行病学情况。
回顾性分析了 1998 年 2 月至 2008 年 1 月期间儿科胃肠病学专科转介的所有 IBD 患儿的病历。
在总共 130 名 IBD 患儿中,92 名(71%)患有克罗恩病,36 名(28%)患有溃疡性结肠炎,2 名(1%)患有未定型结肠炎。IBD 的估计年发病率为 2.16/105/年。年龄范围为 9 个月至 15 岁(中位数:11 岁)。所有患者中有 53%为女性,77%为科威特国民。23%的患者有阳性家族史。最常见的首发症状为腹痛(87%)和腹泻(82%)。就诊时发现有 35%的患儿生长迟缓,20%的患儿身材矮小。在克罗恩病患者中,回结肠部位是最常见的受累部位,而溃疡性结肠炎中最常见的是全结肠炎。
在我们的儿童中,IBD 并不罕见。与西方世界相比,我们发现其临床表现和临床特征没有差异。