Chrysohoou Christina, Pitsavos Christos, Metallinos George, Antoniou Christos, Oikonomou Evaggelos, Kotroyiannis Iason, Tsantilas Apostolis, Tsitsinakis George, Tousoulis Dimitris, Panagiotakos Demosthenes B, Stefanadis Christodoulos
First Cardiology Clinic, School of Medicine, University of Athens, 46 Paleon Polemiston St., Glyfada, 166-74, Athens, Greece.
Heart Vessels. 2012 Nov;27(6):576-84. doi: 10.1007/s00380-011-0190-9. Epub 2011 Sep 27.
Systolic and diastolic functions of both ventricles play a crucial role in the progression of chronic heart failure (CHF). As data about the role of dietary habits in ventricular dysfunction are lacking, we aimed to evaluate the relationship between biventricular diastolic and systolic function and dietary habits in patients with CHF. During 2007, 372 consecutive CHF patients were enrolled. Biventricular systolic and diastolic function was evaluated through echocardiography. Dietary habits were recorded using a food frequency questionnaire, and adherence to a Mediterranean diet was evaluated using the MedDietScore. The MedDietScore was positively correlated with log Smv, left atrial EF and V (p), and inversely correlated with log EA and log Emv/Amv levels (p < 0.05). After adjusting for potential confounders, only log E/A levels were inversely associated with the MedDietScore (p < 0.05). Following analysis per specific aliments, the log E/A ratio was inversely associated with fish intake and olive oil use; the log Emv/Amv ratio was inversely associated with fish intake; log Stv was positively associated with fish, olive oil and pasta intake; log LAKE was positively associated with olive oil use and alcohol drinking (all p < 0.05). This study demonstrated, in a cross-sectional design, a potential beneficial effect of a Mediterranean diet on biventricular systolic and diastolic function.
双心室的收缩和舒张功能在慢性心力衰竭（CHF）的进展中起着关键作用。由于缺乏关于饮食习惯在心室功能障碍中作用的数据，我们旨在评估CHF患者双心室舒张和收缩功能与饮食习惯之间的关系。在2007年期间，连续纳入了372例CHF患者。通过超声心动图评估双心室的收缩和舒张功能。使用食物频率问卷记录饮食习惯，并使用地中海饮食评分（MedDietScore）评估对地中海饮食的依从性。MedDietScore与log Smv、左心房射血分数和V（p）呈正相关，与log EA和log Emv/Amv水平呈负相关（p<0.05）。在对潜在混杂因素进行校正后，只有log E/A水平与MedDietScore呈负相关（p<0.05）。按照特定食物进行分析后，log E/A比值与鱼类摄入量和橄榄油使用量呈负相关；log Emv/Amv比值与鱼类摄入量呈负相关；log Stv与鱼类、橄榄油和面食摄入量呈正相关；log LAKE与橄榄油使用量和饮酒呈正相关（所有p<0.05）。本研究在横断面设计中证明了地中海饮食对双心室收缩和舒张功能具有潜在的有益作用。
