Institute of Tropical Pathology and Public Health, Federal University of Goias, Brazil.
Am J Trop Med Hyg. 2011 Oct;85(4):732-8. doi: 10.4269/ajtmh.2011.11-0067.
The main objective of this study was to measure the quality of life (QoL) during a dengue episode. We conducted a facility-based survey in central Brazil in 2005 and recruited 372 laboratory-confirmed dengue patients greater than 12 years of age in hospital and ambulatory settings. We administered the World Health Organization QoL instrument approximately 15 days after the onset of symptoms. We used principal component analysis with varimax rotation to identify domains related to QoL. The median age of interviewees was 36 years. Most (85%) reported their general health status as very good or good before the dengue episode. Although ambulatory patients were mainly classified as having dengue fever, 44.8% of hospitalized patients had dengue hemorrhagic fever or intermediate dengue. Principal component analysis identified five principal components related to cognition, sleep and energy, mobility, self-care, pain, and discomfort, which explained 73% of the variability of the data matrix. Hospitalized patients had significantly lower mean scores for dimensions cognition, self-care, and pain than ambulatory patients. This investigation documented the generally poor QoL during a dengue episode caused by the large number of domains affected and significant differences between health care settings.
本研究的主要目的是测量登革热发作期间的生活质量（QoL）。我们于 2005 年在巴西中部进行了一项基于机构的调查，在医院和门诊环境中招募了 372 名年龄大于 12 岁的经实验室确诊的登革热患者。我们在症状出现后约 15 天使用世界卫生组织生活质量工具进行调查。我们使用具有方差极大旋转的主成分分析来确定与生活质量相关的领域。受访者的中位数年龄为 36 岁。大多数（85%）在登革热发作前报告其总体健康状况为非常好或好。尽管门诊患者主要被归类为患有登革热，但 44.8%的住院患者患有登革出血热或中等登革热。主成分分析确定了与认知、睡眠和能量、行动能力、自理、疼痛和不适相关的五个主要成分，这些成分解释了数据矩阵变异性的 73%。与门诊患者相比，住院患者在认知、自理和疼痛方面的平均得分明显较低。这项调查记录了大量受影响领域和医疗保健环境之间存在显著差异导致的登革热发作期间普遍较差的生活质量。
