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通过偏振敏感光学相干断层扫描对人体皮肤各向异性进行体内评估。

In vivo evaluation of human skin anisotropy by polarization-sensitive optical coherence tomography.

作者信息

Sakai Shingo, Yamanari Masahiro, Lim Yiheng, Nakagawa Noriaki, Yasuno Yoshiaki

出版信息

Biomed Opt Express. 2011 Sep 1;2(9):2623-31. doi: 10.1364/BOE.2.002623. Epub 2011 Aug 16.

DOI:10.1364/BOE.2.002623
PMID:21991553
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3184871/
Abstract

We performed an in vivo three-dimensional analysis of anisotropic changes in the dermal birefringence of mechanically deformed human skin using polarization-sensitive optical coherence tomography (PS-OCT). The papillary-dermal birefringence of the forehead increased significantly when the skin was shrunk parallel to the body axis, and decreased significantly when the skin was shrunk perpendicular to the body axis. En-face images of the papillary-dermal birefringence revealed variations among individual subjects, and that both shrinking parallel to and stretching in perpendicular to the body axis promoted the formation of macro rope-like birefringent domains. We found that PS-OCT is useful for understanding anisotropic properties of collagen structure in the skin.

摘要

我们使用偏振敏感光学相干断层扫描（PS-OCT）对机械变形的人体皮肤真皮双折射的各向异性变化进行了体内三维分析。当皮肤沿身体轴线平行收缩时，前额乳头层真皮双折射显著增加；当皮肤沿身体轴线垂直收缩时，前额乳头层真皮双折射显著降低。乳头层真皮双折射的正面图像显示个体之间存在差异，并且沿身体轴线平行收缩和垂直拉伸均促进了宏观绳索状双折射域的形成。我们发现PS-OCT有助于理解皮肤中胶原蛋白结构的各向异性特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/685f72d0c067/boe-2-9-2623-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/7f1b4a9d4b67/boe-2-9-2623-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/4941e0ac6b01/boe-2-9-2623-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/217592f68a66/boe-2-9-2623-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/a64e76d0be38/boe-2-9-2623-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/01aaf3edca53/boe-2-9-2623-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/685f72d0c067/boe-2-9-2623-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/7f1b4a9d4b67/boe-2-9-2623-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/4941e0ac6b01/boe-2-9-2623-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/217592f68a66/boe-2-9-2623-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/a64e76d0be38/boe-2-9-2623-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/01aaf3edca53/boe-2-9-2623-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a121/3184871/685f72d0c067/boe-2-9-2623-g006.jpg

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