Seddik Hassan, Tamzaourte Mouna, Rouibaa Fadoua, Fadlouallah Maha, Benkirane Ahmed
Hepatogastroenterology 2 Unit, Mohamed V Military Hospital, Rabat, Morocco.
Int J Hepatol. 2011;2011:814242. doi: 10.4061/2011/814242. Epub 2010 Dec 19.
Ophthalmologic complications with interferon therapy are rare and usually reversible. The anterior ischemic optic neuropathy is an uncommon complication of interferon treatment. A case of irreversible anterior ischemic optic neuropathy complicating interferon therapy for chronic hepatitis C is reported. We suggest that periodic ophthalmological examinations, including visual acuity and fundus examinations, should be performed to patients with high risk of ocular complications after starting and during treatment. We also suggest that an ophthalmologist would be able to detect these complications. Antiviral treatment should be stopped immediately if severe ophthalmologic complications occur.
干扰素治疗的眼科并发症罕见且通常可逆。前部缺血性视神经病变是干扰素治疗的一种不常见并发症。本文报告了一例慢性丙型肝炎患者在干扰素治疗过程中并发不可逆性前部缺血性视神经病变的病例。我们建议，对于眼部并发症高危患者，在开始治疗后及治疗期间应定期进行眼科检查，包括视力和眼底检查。我们还建议应由眼科医生来检测这些并发症。如果发生严重眼科并发症，应立即停止抗病毒治疗。
