糖尿病患者唾液葡萄糖、免疫球蛋白A及流速的评估：一项病例对照研究。
Evaluation of salivary glucose, IgA and flow rate in diabetic patients: a case-control study.
作者信息
Bakianian Vaziri P, Vahedi M, Mortazavi H, Abdollahzadeh Sh, Hajilooi M
机构信息
Assistant Professor, Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
J Dent (Tehran). 2010 Winter;7(1):13-8. Epub 2010 Mar 31.
OBJECTIVE
An association between diabetes mellitus and alterations in the oral cavity has been noted. In this study, we evaluated differences between salivary IgA, glucose and flow rate in diabetic patients compared with healthy controls.
MATERIALS AND METHODS
Forty patients with type 1 diabetes, 40 patients with type 2 diabetes and 40 healthy controls were selected. Whole unstimulated saliva samples were collected by the standard method and the salivary flow rate was determined. Nephelometric and Pars method were used to measure salivary IgA and salivary glucose concentrations, respectively. Statistical analysis was performed by Chi-square and t test.
RESULTS
There were no significant differences in salivary IgA and glucose concentrations between type 1 and type 2 diabetic patients and their matched control subjects (P>0.05). Salivary flow rate was significantly lower in diabetic patients (P<0.05). In addition, DMFT was higher in diabetic patients than the controls.
CONCLUSION
Determination of salivary constituents may be useful in the description and management of oral findings in diabetic patients.
目的
糖尿病与口腔改变之间的关联已被注意到。在本研究中，我们评估了糖尿病患者与健康对照者唾液中免疫球蛋白A（IgA）、葡萄糖和流速的差异。
材料与方法
选取40例1型糖尿病患者、40例2型糖尿病患者和40例健康对照者。采用标准方法收集全唾液非刺激性样本，并测定唾液流速。分别采用比浊法和Pars法测量唾液IgA和唾液葡萄糖浓度。采用卡方检验和t检验进行统计学分析。
结果
1型和2型糖尿病患者与其匹配的对照者之间唾液IgA和葡萄糖浓度无显著差异（P>0.05）。糖尿病患者的唾液流速显著降低（P<0.05）。此外，糖尿病患者的龋失补牙指数（DMFT）高于对照组。
结论
唾液成分的测定可能有助于描述和管理糖尿病患者的口腔表现。
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