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通过环境清洁应对艰难梭菌感染

Tackling C difficile with environmental cleaning.

作者信息

Carter Yvonne, Barry Deborah

机构信息

The Royal Free Hampstead NHS Trust, London.

出版信息

Nurs Times. 2011;107(36):22-5.

Abstract

BACKGROUND

Chlorine-based cleaning products are often used in acute settings for high-level disinfection of the environment to help control C difficile. However, these products must be used at high concentrations, making them irritant, toxic and corrosive. This means they are inappropriate for the near-patient environment, and can lead to user resistance and non-compliance. More recently, products using peracetic acid and hydrogen peroxide have become available, which are highly effective even under conditions of heavy soiling.

AIM

To determine whether peracetic acid sporicidal wipes could help reduce rates of C difficile at an acute London trust.

METHOD

An observational study of C difficile rates was carried out at an acute London trust between 2006 and 2010. All inpatients aged two years and over were monitored. Chlorine-based cleaning regimens and products were changed to peracetic acid sporicidal wipes in April 2008 and monitored for 18 months. Inpatient bed days were also monitored to ensure findings were not affected by changing patient numbers.

RESULTS

The mean C difficile rate per 1000 patients fell from six to two following the 2008 introduction of the sporicidal wipes. In the first half of 2009, this rate dropped to below two. The overall rate of C difficile infection was reduced by 72% following the introduction of the wipes.

CONCLUSION

The introduction of sporicidal wipes resulted in a significant reduction in C difficile rates. This supports the need to review and enhance traditional environmental cleaning regimens for preventing and controlling C difficile in acute settings

摘要

背景

含氯清洁产品常用于急症环境中对环境进行高水平消毒,以帮助控制艰难梭菌感染。然而,这些产品必须高浓度使用,这使其具有刺激性、毒性和腐蚀性。这意味着它们不适用于患者周边环境,可能导致使用者抵触和不依从。最近,使用过氧乙酸和过氧化氢的产品已经面市,即使在污染严重的情况下也非常有效。

目的

确定过氧乙酸杀孢子擦拭布是否有助于降低伦敦一家急症信托医院的艰难梭菌感染率。

方法

2006年至2010年期间,在伦敦一家急症信托医院开展了一项关于艰难梭菌感染率的观察性研究。对所有两岁及以上的住院患者进行监测。2008年4月,将基于氯的清洁方案和产品更换为过氧乙酸杀孢子擦拭布,并持续监测18个月。同时监测住院天数,以确保研究结果不受患者数量变化的影响。

结果

2008年引入杀孢子擦拭布后,每1000名患者的艰难梭菌感染率均值从6降至2。在2009年上半年,该感染率降至2以下。引入擦拭布后,艰难梭菌感染的总体发生率降低了72%。

结论

引入杀孢子擦拭布后,艰难梭菌感染率显著降低。这支持了有必要对传统的环境清洁方案进行审查和强化,以预防和控制急症环境中的艰难梭菌感染。

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