Taub Amy Forman, Garretson Cara Beth
J Clin Aesthet Dermatol. 2011 Oct;4(10):18-27.
This study evaluated the safety and efficacy of sublative fractional bipolar radiofrequency and bipolar radio frequency combined with diode laser for the treatment of both superficial and deep acne scars in patients with skin types II to V.
Prospective, single-center study. Subjects received up to five treatments with sublative fractional bipolar radiofrequency and bipolar radiofrequency combined with diode laser. Treatments were directed to at least two facial (forehead, perioral, cheeks) and/or neck areas with acne scars at four-week intervals. Treatment parameters on each subject were based on skin type and on skin responses to test spots on the target area just before treatment.
Physician office.
Subjects (n=20, aged 40.7±10.5 years [mean ± SD], skin types II-V) with acne scars and without acne lesions enrolled in this prospective study.
RESULTS were evaluated just before each treatment and at four and 12 weeks after the final treatment using the Goodman Scar Scale, a quantitative method of evaluating scars that attempts to reduce grading subjectivity, as well as by patient satisfaction.
Acne scars improved significantly one month after three treatments and improvement persisted for at least 12 weeks after the fifth treatment. Improvement was not affected by skin type. Adverse effects were limited to transient erythema and edema.
The combination of diode laser and bipolar radiofrequency energy device in addition to fractionated sublative radiofrequency is a safe and statistically significantly effective combined modality for the treatment of both superficial and deep acne scars in patients with skin types II to V with minimal downtime and no significant side effects.
本研究评估了非剥脱性双极射频及双极射频联合半导体激光治疗Ⅱ至Ⅴ型皮肤患者浅表和深部痤疮瘢痕的安全性和有效性。
前瞻性单中心研究。受试者接受多达5次非剥脱性双极射频及双极射频联合半导体激光治疗。治疗针对至少两个有痤疮瘢痕的面部(前额、口周、脸颊)和/或颈部区域,间隔4周进行一次。每个受试者的治疗参数基于皮肤类型以及治疗前对目标区域测试点的皮肤反应。
医生办公室。
20名受试者(年龄40.7±10.5岁[均值±标准差],皮肤类型为Ⅱ至Ⅴ型),患有痤疮瘢痕但无痤疮皮损,参与了这项前瞻性研究。
在每次治疗前以及最后一次治疗后4周和12周,使用古德曼瘢痕量表(一种评估瘢痕的定量方法,旨在减少分级主观性)以及患者满意度来评估结果。
三次治疗后1个月痤疮瘢痕有显著改善,第五次治疗后改善持续至少12周。改善情况不受皮肤类型影响。不良反应仅限于短暂的红斑和水肿。
除了分次非剥脱性射频外,半导体激光和双极射频能量设备联合使用,对于治疗Ⅱ至Ⅴ型皮肤患者的浅表和深部痤疮瘢痕是一种安全且具有统计学显著疗效的联合治疗方式,停机时间短且无明显副作用。