Department of Physiotherapy, University of Applied Sciences Leiden, Zernikedreef 11, PO Box 382, 2300 AJ, Leiden, The Netherlands.
Qual Life Res. 2012 Aug;21(6):925-44. doi: 10.1007/s11136-011-0009-2. Epub 2011 Oct 20.
To critically appraise, compare and summarize the measurement properties of self-report fatigue questionnaires validated in patients with multiple sclerosis (MS), Parkinson's disease (PD) or stroke.
MEDLINE, EMBASE, PsycINFO, CINAHL and SPORTdiscus were searched. The COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist was used to assess the methodological quality of studies. A qualitative data synthesis was performed to rate the measurement properties for each questionnaire.
Thirty-eight studies out of 5,336 records met the inclusion criteria, evaluating 31 questionnaires. Moderate evidence was found for adequate internal consistency and structural validity of the Fatigue Scale for Motor and Cognitive functions (FSMC) and for adequate reliability and structural validity of the Unidimensional Fatigue Impact Scale (U-FIS) in MS.
We recommend the FSMC and U-FIS in MS. The Functional Assessment of Chronic Illness Therapy Fatigue subscale (FACIT-F) and Fatigue Severity Scale (FSS) show promise in PD, and the Profile of Mood States Fatigue subscale (POMS-F) for stroke. Future studies should focus on measurement error, responsiveness and interpretability. Studies should also put emphasis on providing input for the theoretical construct of fatigue, allowing the development of questionnaires that reflect generic and disease-specific symptoms of fatigue.
批判性评价、比较和总结在多发性硬化症（MS）、帕金森病（PD）或中风患者中验证的自评疲劳问卷的测量特性。
检索 MEDLINE、EMBASE、PsycINFO、CINAHL 和 SPORTdiscus。使用共识基础的健康测量仪器选择标准（COSMIN）清单评估研究的方法学质量。对每个问卷的测量特性进行定性数据综合评价。
从 5336 条记录中筛选出 38 项符合纳入标准的研究，评估了 31 个问卷。在 MS 中，发现疲劳量表用于运动和认知功能（FSMC）具有足够的内部一致性和结构有效性，以及多维疲劳影响量表（U-FIS）具有足够的可靠性和结构有效性的中度证据。
我们建议在 MS 中使用 FSMC 和 U-FIS。慢性疾病治疗疲劳量表（FACIT-F）和疲劳严重程度量表（FSS）在 PD 中显示出一定的前景，而状态-特质焦虑问卷疲劳分量表（POMS-F）在中风中也有一定的前景。未来的研究应侧重于测量误差、反应性和可解释性。研究还应强调为疲劳的理论结构提供投入，以开发反映疲劳的一般和特定疾病症状的问卷。
