Gatermann Sören G
Abteilung für Medizinische Mikrobiologie, Ruhr-Universität Bochum, Germany.
Transfus Med Hemother. 2011;38(4):236-238. doi: 10.1159/000330425. Epub 2011 Jul 12.
Bacterial contaminations of blood products often originate from the flora of the donor. Normally, components of the skin flora less frequently give rise to severe or complicated infections, although their participation in such conditions has been described. In contrast, bacteria that can cause infections in immunocompetent persons may give rise to life-threatening infections when present in blood products. The latter microorganisms are well-equipped with a variety of virulence factors that contribute to their pathogenicity.
血液制品的细菌污染通常源于献血者的菌群。正常情况下,皮肤菌群成分较少引发严重或复杂感染,尽管已有关于它们参与此类情况的描述。相比之下,能在免疫功能正常者中引起感染的细菌,若存在于血液制品中,则可能引发危及生命的感染。后一类微生物具备多种有助于其致病性的毒力因子。