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Molecular biology of penicillin and cephalosporin biosynthesis.

作者信息

Queener S W

机构信息

Cell Culture Research & Development, Eli Lilly & Company, Indianapolis, Indiana 46285.

出版信息

Antimicrob Agents Chemother. 1990 Jun;34(6):943-8. doi: 10.1128/AAC.34.6.943.

DOI:10.1128/AAC.34.6.943
PMID:2203307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC171734/
Abstract
摘要

相似文献

1
Molecular biology of penicillin and cephalosporin biosynthesis.青霉素和头孢菌素生物合成的分子生物学
Antimicrob Agents Chemother. 1990 Jun;34(6):943-8. doi: 10.1128/AAC.34.6.943.
2
Enzymes involved in penicillin, cephalosporin and cephamycin biosynthesis.
Adv Biochem Eng Biotechnol. 1989;39:153-87. doi: 10.1007/BFb0051954.
3
Organization and expression in Pseudomonas putida of the gene cluster involved in cephalosporin biosynthesis from Lysobacter lactamgenus YK90.来自产内酰胺溶杆菌属YK90的头孢菌素生物合成相关基因簇在恶臭假单胞菌中的组织与表达
Appl Microbiol Biotechnol. 1996 May;45(4):490-501. doi: 10.1007/BF00578461.
4
Expression of genes and processing of enzymes for the biosynthesis of penicillins and cephalosporins.青霉素和头孢菌素生物合成相关基因的表达及酶的加工过程。
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5
The enzymes involved in biosynthesis of penicillin and cephalosporin; their structure and function.
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6
New aspects of genes and enzymes for beta-lactam antibiotic biosynthesis.β-内酰胺抗生素生物合成中基因与酶的新进展。
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7
Molecular control of expression of penicillin biosynthesis genes in fungi: regulatory proteins interact with a bidirectional promoter region.真菌中青霉素生物合成基因表达的分子调控：调控蛋白与双向启动子区域相互作用。
J Bacteriol. 2000 May;182(9):2355-62. doi: 10.1128/JB.182.9.2355-2362.2000.
8
Biochemistry and molecular genetics of penicillin production in Penicillium chrysogenum.
Ann N Y Acad Sci. 1991 Dec 27;646:193-201. doi: 10.1111/j.1749-6632.1991.tb18577.x.
9
Enzymatic synthesis of the penicillin and cephalosporin nuclei from an acyclic peptide containing carboxymethylcysteine.
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Isolation of deacetoxycephalosporin C from fermentation broths of Penicillium chrysogenum transformants: construction of a new fungal biosynthetic pathway.从产黄青霉转化体发酵液中分离去乙酰氧基头孢菌素C：构建新的真菌生物合成途径。
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Regulation of the Aspergillus nidulans penicillin biosynthesis gene acvA (pcbAB) by amino acids: implication for involvement of transcription factor PACC.氨基酸对构巢曲霉青霉素生物合成基因acvA（pcbAB）的调控：转录因子PACC参与的意义。
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Analysis of the regulation of the Aspergillus nidulans penicillin biosynthesis gene aat (penDE), which encodes acyl coenzyme A:6-aminopenicillanic acid acyltransferase.构巢曲霉青霉素生物合成基因aat（penDE）的调控分析，该基因编码酰基辅酶A：6-氨基青霉烷酸酰基转移酶。
Mol Gen Genet. 1995 Dec 15;249(5):557-69. doi: 10.1007/BF00290581.
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Cloning of a Streptomyces clavuligerus DNA fragment encoding the cephalosporin 7 alpha-hydroxylase and its expression in Streptomyces lividans.编码头孢菌素7α-羟化酶的棒状链霉菌DNA片段的克隆及其在淡紫链霉菌中的表达。
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Cloning, characterization, and use in strain improvement of the Cephalosporium acremonium gene cefG encoding acetyl transferase.顶头孢霉编码乙酰转移酶的基因cefG的克隆、特性分析及其在菌株改良中的应用
Curr Genet. 1993 Jan;23(1):33-41. doi: 10.1007/BF00336747.

本文引用的文献

1
Studies on the ring-cyclization and ring-expansion enzymes of beta-lactam biosynthesis in Cephalosporium acremonium.顶头孢霉中β-内酰胺生物合成的环化和扩环酶研究。
Can J Microbiol. 1983 May;29(5):488-96. doi: 10.1139/m83-078.
2
Partial purification and catalytic properties of a bifunctional enzyme in the biosynthetic pathway of beta-lactams in Cephalosporium acremonium.顶头孢霉中β-内酰胺生物合成途径中一种双功能酶的部分纯化及催化特性
J Antibiot (Tokyo). 1984 May;37(5):522-31. doi: 10.7164/antibiotics.37.522.
3
Purification of isopenicillin N synthetase.异青霉素N合成酶的纯化
Biochem J. 1984 Sep 15;222(3):789-95. doi: 10.1042/bj2220789.
4
Enzymatic approach to syntheses of unnatural beta-lactams.
Science. 1984 Dec 21;226(4681):1386-92. doi: 10.1126/science.6390683.
5
Penicillin acyltransferase in Penicillium chrysogenum.产黄青霉中的青霉素酰基转移酶。
J Bacteriol. 1967 Nov;94(5):1502-8. doi: 10.1128/jb.94.5.1502-1508.1967.
6
Deacetoxycephalosporin C synthetase and deacetoxycephalosporin C hydroxylase are two separate enzymes in Streptomyces clavuligerus.去乙酰氧基头孢菌素C合成酶和去乙酰氧基头孢菌素C羟化酶是棒状链霉菌中的两种不同的酶。
J Antibiot (Tokyo). 1985 Feb;38(2):263-5. doi: 10.7164/antibiotics.38.263.
7
Isolation, sequence determination and expression in Escherichia coli of the isopenicillin N synthetase gene from Cephalosporium acremonium.顶头孢霉异青霉素N合成酶基因的分离、序列测定及在大肠杆菌中的表达
Nature. 1985;318(6042):191-4. doi: 10.1038/318191a0.
8
Copurification and characterization of deacetoxycephalosporin C synthetase/hydroxylase from Cephalosporium acremonium.顶头孢霉中去乙酰氧基头孢菌素C合成酶/羟化酶的共纯化及特性研究
J Bacteriol. 1987 Apr;169(4):1611-8. doi: 10.1128/jb.169.4.1611-1618.1987.
9
Effects of beta-lactam antibiotics on proliferating eucaryotic cells.β-内酰胺类抗生素对增殖真核细胞的影响。
Antimicrob Agents Chemother. 1987 Nov;31(11):1657-61. doi: 10.1128/AAC.31.11.1657.
10
Cloning and characterization of the isopenicillin N synthetase gene mediating the formation of the beta-lactam ring in Aspergillus nidulans.构巢曲霉中介导β-内酰胺环形成的异青霉素N合成酶基因的克隆与鉴定
Gene. 1987;57(2-3):171-81. doi: 10.1016/0378-1119(87)90120-x.