Yun James, Katelaris Constance H, Weerasinghe Anura, Adikari Duminda Bandara, Ratnayake Chanaka
Campbelltown Hospital, Campbelltown NSW 2560, Australia.
Asia Pac Allergy. 2011 Apr;1(1):25-9. doi: 10.5415/apallergy.2011.1.1.25. Epub 2011 Apr 20.
Chronic idiopathic urticaria (CIU) has a significant impact on patients' quality of life.
The purpose of this study is to assess that impact and to compare differences by culture, gender, age or duration of treatment.
We used the modified chronic urticaria quality of life questionnaire, consisting of 15 questions. Over the course of 6 months, patients attending Immunology clinics at Campbelltown Hospital and private rooms in Australia and at the faculty of Medicine, University of Kelaniya in Sri Lanka were asked to fill out the questionnaires. We have obtained the data from 125 patients (43 Australian vs. 82 Sri Lankan). There were significantly more female patients (P < 0.01). The data was analysed using SAS.
Overall, patients were affected mostly by itch and wheals and least affected by the side effects of treatments. Sri Lankan populations were more affected by wheals and by interference on activities, mood and food choices but were less affected by tiredness due to sleep disturbances (P < 0.01). Females were more affected by sleep disturbance (P < 0.05) while those older than 40 years of age were more impacted by tiredness and by the side effects from medications (P < 0.05), though the complaints themselves were mild. Those who suffered from CIU for more than 1 year were more affected by wheal, tiredness and irritability (P ≤ 0.05).
The questionnaire highlighted some differences between patients attending Australian versus Sri Lankan outpatients. Significant differences were found in one third of parameters which include mood, sleep, daily activities and food choices.
慢性特发性荨麻疹（CIU）对患者的生活质量有重大影响。
本研究旨在评估这种影响，并比较不同文化、性别、年龄或治疗持续时间之间的差异。
我们使用了改良的慢性荨麻疹生活质量问卷，该问卷由15个问题组成。在6个月的时间里，我们邀请了在澳大利亚坎贝尔敦医院免疫科诊所、澳大利亚私人诊室以及斯里兰卡凯拉尼亚大学医学院就诊的患者填写问卷。我们收集了125名患者的数据（43名澳大利亚患者和82名斯里兰卡患者）。女性患者明显更多（P < 0.01）。数据使用SAS进行分析。
总体而言，患者受瘙痒和风团影响最大，受治疗副作用影响最小。斯里兰卡人群受风团以及对活动、情绪和食物选择的干扰影响更大，但受睡眠障碍导致的疲劳影响较小（P < 0.01）。女性受睡眠障碍影响更大（P < 0.05），而40岁以上的患者受疲劳和药物副作用影响更大（P < 0.05），不过这些不适本身较轻。患CIU超过1年的患者受风团、疲劳和易怒影响更大（P≤0.05）。
该问卷突出了澳大利亚和斯里兰卡门诊患者之间的一些差异。在包括情绪、睡眠、日常活动和食物选择在内的三分之一参数中发现了显著差异。
