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WHO guidelines for the programmatic management of drug-resistant tuberculosis: 2011 update.世卫组织耐药结核病规划管理指南：2011 年更新版。
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Epidemiology of antituberculosis drug resistance 2002-07: an updated analysis of the Global Project on Anti-Tuberculosis Drug Resistance Surveillance.2002 - 2007年抗结核药物耐药性流行病学：全球抗结核药物耐药性监测项目的最新分析
Lancet. 2009 May 30;373(9678):1861-73. doi: 10.1016/S0140-6736(09)60331-7. Epub 2009 Apr 15.
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Multicenter laboratory evaluation of the MB/BacT Mycobacterium detection system and the BACTEC MGIT 960 system in comparison with the BACTEC 460TB system for susceptibility testing of Mycobacterium tuberculosis.MB/BacT分枝杆菌检测系统和BACTEC MGIT 960系统与BACTEC 460TB系统用于结核分枝杆菌药敏试验的多中心实验室评估。
J Clin Microbiol. 2007 Jun;45(6):1766-70. doi: 10.1128/JCM.02162-06. Epub 2007 Apr 18.
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Epidemiology of antituberculosis drug resistance (the Global Project on Anti-tuberculosis Drug Resistance Surveillance): an updated analysis.抗结核药物耐药性流行病学（全球抗结核药物耐药性监测项目）：最新分析
Lancet. 2006 Dec 16;368(9553):2142-54. doi: 10.1016/S0140-6736(06)69863-2.
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Current perspectives on drug susceptibility testing of Mycobacterium tuberculosis complex: the automated nonradiometric systems.结核分枝杆菌复合群药敏试验的当前观点：自动化非放射性系统
J Clin Microbiol. 2006 Jan;44(1):20-8. doi: 10.1128/JCM.44.1.20-28.2006.
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Comparison of BACTEC MGIT 960 system and BACTEC 460 TB system for growth and detection of Mycobacteria from clinical specimens.BACTEC MGIT 960系统与BACTEC 460结核系统用于临床标本中分枝杆菌生长与检测的比较
Malays J Pathol. 2004 Dec;26(2):99-103.
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Evaluation of the fully automated BACTEC MGIT 960 system for testing susceptibility of Mycobacterium tuberculosis to pyrazinamide, streptomycin, isoniazid, rifampin, and ethambutol and comparison with the radiometric BACTEC 460TB method.评估全自动BACTEC MGIT 960系统检测结核分枝杆菌对吡嗪酰胺、链霉素、异烟肼、利福平和乙胺丁醇的药敏性，并与放射性BACTEC 460TB方法进行比较。
J Clin Microbiol. 2004 Mar;42(3):1109-14. doi: 10.1128/JCM.42.3.1109-1114.2004.
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Quality assurance programme for drug susceptibility testing of Mycobacterium tuberculosis in the WHO/IUATLD Supranational Reference Laboratory Network: five rounds of proficiency testing, 1994-1998.世界卫生组织/国际防痨和肺部疾病联盟超国家参考实验室网络中结核分枝杆菌药敏试验的质量保证计划：1994 - 1998年的五轮能力验证试验
Int J Tuberc Lung Dis. 2002 Sep;6(9):748-56.
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Comparison of the ESP and BACTEC systems for testing susceptibilities of Mycobacterium tuberculosis complex isolates to pyrazinamide.用于检测结核分枝杆菌复合群分离株对吡嗪酰胺药敏性的ESP系统和BACTEC系统的比较。
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Evaluation of automated BACTEC MGIT 960 system for testing susceptibility of Mycobacterium tuberculosis to four major antituberculous drugs: comparison with the radiometric BACTEC 460TB method and the agar plate method of proportion.评估自动BACTEC MGIT 960系统检测结核分枝杆菌对四种主要抗结核药物敏感性的能力：与放射性BACTEC 460TB方法及比例琼脂平板法的比较
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评价 VersaTREK 系统与 Bactec MGIT 960 系统在结核分枝杆菌一线药物敏感性检测中的应用。

Evaluation of the VersaTREK system compared to the Bactec MGIT 960 system for first-line drug susceptibility testing of Mycobacterium tuberculosis.

机构信息

Laboratori de Microbiologia, UDIAT-CD, Corporació Sanitària Parc Taulí, Sabadell, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Barcelona, Spain.

出版信息

J Clin Microbiol. 2012 Feb;50(2):488-91. doi: 10.1128/JCM.06432-11. Epub 2011 Nov 30.

DOI:10.1128/JCM.06432-11
PMID:22135258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3264154/
Abstract

The aim of this study was to evaluate the reliability of the VersaTREK system for Mycobacterium tuberculosis drug susceptibility testing compared with results obtained with the Bactec MGIT 960 system. A total of 67 strains were evaluated. Overall agreement was at 98.5%. Kappa indexes were 1.0 for isoniazid, rifampin, and ethambutol, 0.937 for pyrazinamide, and 0.907 for streptomycin. The VersaTREK system is validated for M. tuberculosis drug susceptibility testing.

摘要

本研究旨在评估 VersaTREK 系统与 Bactec MGIT 960 系统相比，用于结核分枝杆菌药物敏感性检测的可靠性。共评估了 67 株菌株。总体符合率为 98.5%。异烟肼、利福平、乙胺丁醇的 Kappa 指数为 1.0，吡嗪酰胺为 0.937，链霉素为 0.907。VersaTREK 系统已验证可用于结核分枝杆菌药物敏感性检测。