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感染梅毒螺旋体的兔睾丸中炎症细胞的免疫活性

Immunocompetence of inflammatory cells in rabbit testes infected with Treponema pallidum.

作者信息

Wicher V, Wicher K

机构信息

Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany 12201-0509.

出版信息

J Reprod Immunol. 1990 Aug;18(1):105-15. doi: 10.1016/0165-0378(90)90027-4.

DOI:10.1016/0165-0378(90)90027-4
PMID:2213728
Abstract

Systematic studies were conducted in rabbits to delineate factors favoring the predilection for multiplication of T. pallidum in testes. The results strongly suggest that, in addition to the mucoid material produced during lesion development regardless of the site of infection, a whole array of testicular substances with immunomodulatory activity may largely contribute to the propagation and delayed clearance of the pathogen from the testicular environment and most likely from the host.

摘要

在兔子身上进行了系统研究,以确定有利于梅毒螺旋体在睾丸中增殖的因素。结果有力地表明,除了在病变发展过程中产生的黏液样物质(无论感染部位如何)外,一系列具有免疫调节活性的睾丸物质可能在很大程度上有助于病原体在睾丸环境中以及很可能在宿主体内的繁殖和延迟清除。

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Immunocompetence of inflammatory cells in rabbit testes infected with Treponema pallidum.感染梅毒螺旋体的兔睾丸中炎症细胞的免疫活性
J Reprod Immunol. 1990 Aug;18(1):105-15. doi: 10.1016/0165-0378(90)90027-4.
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Studies of rabbit testes infected with Treponema pallidum. I Immunopathology.感染梅毒螺旋体的兔睾丸研究。I. 免疫病理学
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Avoidance of host defences by Treponema pallidum in situ and on extraction from infected rabbit testes.梅毒螺旋体在原位以及从受感染兔睾丸中提取出来后对宿主防御的规避。
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