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从污水处理厂细菌群落中不同类型质粒上回收的碳青霉烯水解 GES-5 编码基因。

Carbapenem-hydrolyzing GES-5-encoding gene on different plasmid types recovered from a bacterial community in a sewage treatment plant.

机构信息

Service de Bactériologie-Virologie, INSERM U914, Emerging Resistance to Antibiotics, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris Sud, Le Kremlin-Bicêtre, France.

出版信息

Appl Environ Microbiol. 2012 Feb;78(4):1292-5. doi: 10.1128/AEM.06841-11. Epub 2011 Dec 9.

Abstract

Plasmids pRSB113 and pRSB115 were recovered from an activated sludge bacterial community of a municipal wastewater treatment plant in Germany. Both plasmids carry the same bla(GES-5) carbapenemase gene, located within two distinct class 1 integrons. These plasmids have different backbones, belong to different incompatibility groups, and could replicate in both Pseudomonas aeruginosa and Escherichia coli.

摘要

质粒 pRSB113 和 pRSB115 是从德国一个城市污水处理厂的活性污泥细菌群落中回收的。这两个质粒都携带相同的 bla(GES-5)碳青霉烯酶基因,位于两个不同的 class 1 整合子内。这些质粒具有不同的骨架,属于不同的不相容群,可以在铜绿假单胞菌和大肠杆菌中复制。

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