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Detection of GES-5 Carbapenemase in Klebsiella pneumoniae, a Newcomer in France.法国新发现的肺炎克雷伯菌中GES-5碳青霉烯酶的检测
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2
First report of OXA-232-producing Klebsiella pneumoniae strains in Tunisia.突尼斯产OXA-232肺炎克雷伯菌菌株的首次报告。
Diagn Microbiol Infect Dis. 2017 Jun;88(2):195-197. doi: 10.1016/j.diagmicrobio.2017.03.005. Epub 2017 Mar 11.
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Characterization of Carbapenemase-Producing in Clinical Center University of Sarajevo, Bosnia and Herzegovina.在波斯尼亚和黑塞哥维那萨拉热窝大学临床中心对产碳青霉烯酶的研究。
Microb Drug Resist. 2020 Sep;26(9):1038-1045. doi: 10.1089/mdr.2019.0188. Epub 2020 Mar 25.
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Emergence of Klebsiella pneumoniae ST273 Carrying bla and ST656 Carrying bla in Manila, Philippines.菲律宾马尼拉出现携带bla的肺炎克雷伯菌ST273和携带bla的ST656。
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Plasmid-mediated carbapenem-hydrolysing β-lactamase KPC-2 in a Klebsiella pneumoniae isolate from Switzerland.瑞士一株肺炎克雷伯菌分离株中质粒介导的碳青霉烯水解β-内酰胺酶KPC-2
J Antimicrob Chemother. 2011 Mar;66(3):675-6. doi: 10.1093/jac/dkq499. Epub 2010 Dec 29.
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Genomic Characterization of Carbapenemase-Producing Klebsiella pneumoniae with Chromosomally Carried .产碳青霉烯酶肺炎克雷伯菌的染色体携带. 基因的基因组特征
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Novel NDM-9 metallo-β-lactamase identified from a ST107 Klebsiella pneumoniae strain isolated in China.从中国分离出的一株ST107肺炎克雷伯菌中鉴定出新型NDM-9金属β-内酰胺酶。
Int J Antimicrob Agents. 2014 Jul;44(1):90-1. doi: 10.1016/j.ijantimicag.2014.04.010. Epub 2014 May 21.
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A Two-Year Surveillance in Five Colombian Tertiary Care Hospitals Reveals High Frequency of Non-CG258 Clones of Carbapenem-Resistant Klebsiella pneumoniae with Distinct Clinical Characteristics.在五家哥伦比亚三级护理医院进行的为期两年的监测显示，耐碳青霉烯类肺炎克雷伯菌的非CG258克隆株出现频率较高，且具有不同的临床特征。
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Prevalence of a New Variant OXA-204 and OXA-48 Carbapenemases Plasmids Encoded in Klebsiella pneumoniae Clinical Isolates in Tunisia.突尼斯肺炎克雷伯菌临床分离株中编码新型OXA-204和OXA-48碳青霉烯酶质粒的流行情况。
Microb Drug Resist. 2018 Mar;24(2):142-149. doi: 10.1089/mdr.2016.0236. Epub 2017 Jul 24.
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Plasmid-mediated carbapenem-hydrolysing OXA-48 beta-lactamase in Klebsiella pneumoniae from Tunisia.突尼斯肺炎克雷伯菌中质粒介导的碳青霉烯水解OXA-48β-内酰胺酶
Int J Antimicrob Agents. 2010 Jul;36(1):91-3. doi: 10.1016/j.ijantimicag.2010.02.014. Epub 2010 Mar 30.

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Virulence factors in carbapenem-resistant hypervirulent .耐碳青霉烯类高毒力菌中的毒力因子
Front Microbiol. 2023 Nov 30;14:1325077. doi: 10.3389/fmicb.2023.1325077. eCollection 2023.
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Genetic Diversity, Biochemical Properties, and Detection Methods of Minor Carbapenemases in Enterobacterales.肠杆菌科细菌中碳青霉烯类小酶的遗传多样性、生化特性及检测方法
Front Med (Lausanne). 2021 Jan 20;7:616490. doi: 10.3389/fmed.2020.616490. eCollection 2020.
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Dissemination Pattern of Multidrug Resistant Carbapenemase Producing Isolates Using Pulsed-Field Gel Electrophoresis in Southwestern Iran.伊朗西南部地区产多重耐药碳青霉烯酶菌株的脉冲场凝胶电泳传播模式
Infect Drug Resist. 2020 Mar 30;13:921-929. doi: 10.2147/IDR.S227955. eCollection 2020.
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Development of a Two Triplex Real-Time Polymerase Chain Reaction for Rapid Detection of Six Carbapenemase Genes in Enterobacteriaceae.用于快速检测肠杆菌科六种碳青霉烯酶基因的双三重实时聚合酶链反应的开发
Osong Public Health Res Perspect. 2020 Feb;11(1):53-59. doi: 10.24171/j.phrp.2020.11.1.08.
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Targeting the Class A Carbapenemase GES-5 via Virtual Screening.通过虚拟筛选靶向 A 类碳青霉烯酶 GES-5。
Biomolecules. 2020 Feb 14;10(2):304. doi: 10.3390/biom10020304.
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Epidemiology of Carbapenemase-Producing Klebsiella pneumoniae in a Hospital, Portugal.葡萄牙一家医院中产碳青霉烯酶肺炎克雷伯菌的流行病学研究。
Emerg Infect Dis. 2019 Sep;25(9):1632-1638. doi: 10.3201/eid2509.190656.
7
Development of a Novel Loop-Mediated Isothermal Amplification Method to Detect Guiana Extended-Spectrum (GES) β-Lactamase Genes in .一种用于检测 [具体对象] 中圭亚那超广谱（GES）β-内酰胺酶基因的新型环介导等温扩增方法的开发 。 （注：原文中“in”后面缺少具体内容）
Front Microbiol. 2019 Feb 4;10:25. doi: 10.3389/fmicb.2019.00025. eCollection 2019.
8
First virtual screening and experimental validation of inhibitors targeting GES-5 carbapenemase.针对 GES-5 碳青霉烯酶的抑制剂的首次虚拟筛选和实验验证。
J Comput Aided Mol Des. 2019 Feb;33(2):295-305. doi: 10.1007/s10822-018-0182-2. Epub 2019 Jan 2.

本文引用的文献

1
Comparative Evaluation of Four Phenotypic Tests for Detection of Carbapenemase-Producing Gram-Negative Bacteria.用于检测产碳青霉烯酶革兰氏阴性菌的四种表型试验的比较评估
J Clin Microbiol. 2017 Feb;55(2):510-518. doi: 10.1128/JCM.01853-16. Epub 2016 Dec 7.
2
Clonal Dissemination of Pseudomonas aeruginosa Sequence Type 235 Isolates Carrying blaIMP-6 and Emergence of blaGES-24 and blaIMP-10 on Novel Genomic Islands PAGI-15 and -16 in South Korea.韩国携带blaIMP-6的235型铜绿假单胞菌分离株的克隆传播以及新型基因组岛PAGI-15和-16上blaGES-24和blaIMP-10的出现
Antimicrob Agents Chemother. 2016 Nov 21;60(12):7216-7223. doi: 10.1128/AAC.01601-16. Print 2016 Dec.
3
Spread of Plasmids Carrying Multiple GES Variants.携带多种GES变体的质粒的传播。
Antimicrob Agents Chemother. 2016 Jul 22;60(8):5040-3. doi: 10.1128/AAC.00360-16. Print 2016 Aug.
4
Improvement of the Xpert Carba-R Kit for the Detection of Carbapenemase-Producing Enterobacteriaceae.用于检测产碳青霉烯酶肠杆菌科细菌的Xpert Carba - R试剂盒的改进
Antimicrob Agents Chemother. 2016 May 23;60(6):3832-7. doi: 10.1128/AAC.00517-16. Print 2016 Jun.
5
Structural and Functional Aspects of Class A Carbapenemases.A类碳青霉烯酶的结构与功能方面
Curr Drug Targets. 2016;17(9):1006-28. doi: 10.2174/1389450117666160310144501.
6
Draft Genome Sequence of the Serratia rubidaea CIP 103234T Reference Strain, a Human-Opportunistic Pathogen.人机会致病菌深红沙雷氏菌CIP 103234T参考菌株的基因组序列草图
Genome Announc. 2015 Nov 19;3(6):e01340-15. doi: 10.1128/genomeA.01340-15.
7
Evaluation of the RAPIDEC® CARBA NP, the Rapid CARB Screen® and the Carba NP test for biochemical detection of carbapenemase-producing Enterobacteriaceae.评估用于生化检测产碳青霉烯酶肠杆菌科细菌的RAPIDEC® CARBA NP、Rapid CARB Screen®和Carba NP检测方法。
J Antimicrob Chemother. 2015 Nov;70(11):3014-22. doi: 10.1093/jac/dkv213. Epub 2015 Aug 9.
8
Efficient Detection of Carbapenemase Activity in Enterobacteriaceae by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry in Less Than 30 Minutes.基质辅助激光解吸电离飞行时间质谱法在30分钟内高效检测肠杆菌科细菌中的碳青霉烯酶活性
J Clin Microbiol. 2015 Jul;53(7):2163-71. doi: 10.1128/JCM.03467-14. Epub 2015 Apr 29.
9
The carbapenem inactivation method (CIM), a simple and low-cost alternative for the Carba NP test to assess phenotypic carbapenemase activity in gram-negative rods.碳青霉烯灭活方法（CIM），是一种简单且低成本的替代方法，可用于替代Carba NP试验来评估革兰氏阴性杆菌中的表型碳青霉烯酶活性。
PLoS One. 2015 Mar 23;10(3):e0123690. doi: 10.1371/journal.pone.0123690. eCollection 2015.
10
Epidemic Klebsiella pneumoniae ST258 is a hybrid strain.流行的肺炎克雷伯菌ST258是一种杂交菌株。
mBio. 2014 Jun 24;5(3):e01355-14. doi: 10.1128/mBio.01355-14.

Detection of GES-5 Carbapenemase in Klebsiella pneumoniae, a Newcomer in France.

作者信息

Bonnin Rémy A, Jousset Agnès B, Urvoy Noémie, Gauthier Lauraine, Tlili Linda, Creton Elodie, Cotellon Garance, Arthur Fabienne, Dortet Laurent, Naas Thierry

机构信息

EA7361, Université Paris-Sud, Université Paris-Saclay, LabEx LERMIT, Bacteriology-Hygiene Unit, APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France

Evolution and Ecology of Resistance to Antibiotics (EERA) Unit, Institut Pasteur, APHP, Université Paris-Sud, Paris, France.

出版信息

Antimicrob Agents Chemother. 2017 Feb 23;61(3). doi: 10.1128/AAC.02263-16. Print 2017 Mar.

DOI:10.1128/AAC.02263-16
PMID:28052846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5328544/
Abstract
摘要