Yadav Vikender S, Narula Satish C, Sharma Rajinder K, Tewari Shikha, Yadav Renu
Department of Periodontics and Oral Implantology, Government Dental College, Rohtak, Haryana, India.
J Oral Sci. 2011 Dec;53(4):481-8. doi: 10.2334/josnusd.53.481.
Conflicting data exist on the combined use of grafting materials and barrier membranes in comparison to guided tissue regeneration (GTR) with membrane alone. The aim of the present study was to compare the clinical outcomes of GTR with collagen membrane (CM) alone (control group) or CM combined with autogenous bone graft (test group 1) or autogenous bone mixed with bioactive glass (test group 2) in intrabony defects. A total of 32 intraosseous defects in 22 subjects were treated randomly. After 6 months, significant probing depth reduction, clinical attachment level gain (CAL) and defect resolution were observed in all groups with significantly greater improvements in the test groups. There was no significant difference between the two test groups in any parameter. Results of the present study suggest that autogenous bone can be mixed with bioactive glass if the amount of the harvested bone is not sufficient.
与仅使用膜的引导组织再生（GTR）相比，关于移植材料和屏障膜联合使用的数据存在冲突。本研究的目的是比较在骨内缺损中单独使用胶原膜（CM）（对照组）或CM与自体骨移植联合使用（试验组1）或自体骨与生物活性玻璃混合使用（试验组2）的GTR临床结果。对22名受试者的32个骨内缺损进行了随机治疗。6个月后，所有组均观察到探诊深度显著降低、临床附着水平增加（CAL）和缺损修复，试验组的改善更为显著。两个试验组在任何参数上均无显著差异。本研究结果表明，如果采集的骨量不足，自体骨可以与生物活性玻璃混合使用。
