School of Optometry, Indiana University, Bloomington, Indiana, USA.
Invest Ophthalmol Vis Sci. 2012 Feb 2;53(2):633-9. doi: 10.1167/iovs.10-6674. Print 2012 Feb.
To characterize contrast sensitivity for sinusoidal stimuli across the central visual field and help bridge the gap between perimetry and visual psychophysics by developing a contrast-sensitivity template for spatial scale (experiment 1) and testing it on a new dataset (experiment 2).
In experiment 1, 40 subjects free of eye disease, ages 43 to 84 years, had one eye tested. Twenty-three locations along the horizontal and vertical meridians were tested with sinusoidal stimuli having peak spatial frequencies of 0.5, 1.0, and 2.0 cpd and a spatial bandwidth of 1.0 octave. Contrast sensitivity functions were fit with a low-pass template slid horizontally on a log-log plot by a spatial scale factor. In experiment 2, 29 of the original subjects had one eye tested. Twenty-six locations in grid form were tested with sinusoidal stimuli having peak spatial frequencies of 0.375, 0.53, 0.75, and 1.5 cpd. Spatial scale values were predicted using the 0.375 cpd data and template and compared to empirical values determined from the remaining data.
In experiment 1, the change in spatial scale alone fit the mean sensitivities well (residual sum of squares = 0.01 log unit). Spatial scale increased with eccentricity except for horizontal nasal displacements between 3° and 15°. In experiment 2, differences between empirical and predicted spatial scale values were within ±0.1 log unit (mean and SEM: 0.00 ± 0.01 log unit).
Spatial scale characterized the visual field tested in perimetry well and can contribute to further linkage between clinical perimetry and basic vision science.
通过开发一种用于空间尺度的对比敏感度模板（实验 1）并在新数据集上进行测试（实验 2），来描述正弦刺激在中央视野中的对比敏感度，并帮助缩小视野计和视觉心理物理学之间的差距。
在实验 1 中，40 名无眼部疾病的受试者（年龄 43 至 84 岁），每只眼睛进行一次测试。使用具有 0.5、1.0 和 2.0 cpd 峰值空间频率和 1.0 个倍频程空间带宽的正弦刺激，在水平和垂直子午线的 23 个位置进行测试。对比敏感度函数通过空间尺度因子在对数-对数图上水平滑动的低通模板进行拟合。在实验 2 中，对 29 名原始受试者中的一只眼睛进行了测试。在网格形式的 26 个位置上，使用具有 0.375、0.53、0.75 和 1.5 cpd 峰值空间频率的正弦刺激进行测试。使用 0.375 cpd 数据和模板预测空间尺度值，并将其与从其余数据确定的经验值进行比较。
在实验 1 中，仅空间尺度的变化就能很好地拟合平均灵敏度（残差平方和= 0.01 对数单位）。空间尺度随离轴距离的增加而增加，但 3°至 15°之间的水平鼻侧位移除外。在实验 2 中，经验值和预测值之间的空间尺度差异在±0.1 对数单位内（平均值和 SEM：0.00 ± 0.01 对数单位）。
空间尺度很好地描述了视野计测试中的视野，可以进一步促进临床视野计和基础视觉科学之间的联系。
