Royal Holloway, University of London, Surrey, UK.
Mult Scler. 2012 Jun;18(6):891-8. doi: 10.1177/1352458511431076. Epub 2011 Dec 21.
Cognitive impairment in MS impacts negatively on many patients at all disease stages and in all subtypes. Full clinical cognitive assessment is expensive, requiring expert staff and special equipment. Test versions and normative data are not available for all languages and cultures.
To recommend a brief cognitive assessment for multiple sclerosis (MS) that is optimized for small centers, with one or few staff members, who may not have neuropsychological training and constructed to maximize international use.
An expert committee of twelve members representing the main cultural groups that have so far contributed considerable data about MS cognitive dysfunction was convened. Following exhaustive literature review, peer-reviewed articles were selected to cover a broad spectrum of cultures and scales that targeted cognitive domains vulnerable to MS. Each was rated by two committee members and candidates scales were rated on psychometric qualities (reliability, validity, and sensitivity), international application, ease of administration, feasibility in the specified context, and acceptability to patients.
The committee recommended the Symbol Digit Modalities Test, if only 5 minutes was available, with the addition of the California Verbal Learning Test - Second Edition and the Brief Visuospatial Memory Test - Revised learning trials if a further 10 minutes could be allocated for testing.
A brief cognitive assessment for MS has been recommended. A validation protocol has been prepared for language groups and validation studies have commenced.
MS 患者的认知障碍在所有疾病阶段和所有亚型中都对许多患者产生负面影响。全面的临床认知评估费用高昂，需要专业人员和特殊设备。并非所有语言和文化都有测试版本和规范数据。
为多发性硬化症（MS）推荐一种简短的认知评估方法，该方法针对的是人员较少的小型中心，这些人员可能没有神经心理学方面的培训，且该方法的构建应最大限度地提高国际适用性。
召集了一个由 12 名成员组成的专家委员会，这些成员代表了迄今为止为 MS 认知功能障碍提供了大量数据的主要文化群体。在进行详尽的文献回顾后，选择了经过同行评审的文章，以涵盖针对易受 MS 影响的认知领域的广泛文化和量表。每个量表都由两名委员会成员进行评分，候选量表则根据心理测量学质量（可靠性、有效性和敏感性）、国际适用性、在指定环境下的可操作性以及患者的可接受性进行评分。
委员会建议，如果只有 5 分钟的时间，可以使用符号数字模态测试，如果可以再分配 10 分钟进行测试，则可以添加加利福尼亚语言学习测试 - 第二版和简短视觉空间记忆测试 - 修订版学习试验。
已经为 MS 推荐了一种简短的认知评估方法。已为语言群体制定了验证方案，并已开始验证研究。
