Roy Chowdhury S K, Ramen Sinha, Chattopadhyay P K, Moorchung N, Rajkumar K
J Maxillofac Oral Surg. 2010 Jun;9(2):198-201. doi: 10.1007/s12663-010-0051-6. Epub 2010 Sep 22.
Odontogenic carcinomas are rare lesions arising from dental embryogenic residues and have been designated by a variety of terms like malignant ameloblastoma, ameloblastic carcinoma, metastatic ameloblastoma or primary intra-alveolar epidermoid carcinoma. Ameloblastic carcinoma combines the histological features of ameloblastoma with cytological atypia, even in the absence of metastasis. The lesion has been reported to arise either from the odontogenic cyst or the ameloblastoma. Majority originate de novo and the remaining are malignant transformation of an ameloblastoma.
牙源性癌是起源于牙齿胚胎残余组织的罕见病变,曾被用多种术语来命名,如恶性成釉细胞瘤、成釉细胞癌、转移性成釉细胞瘤或原发性牙槽内表皮样癌。成釉细胞癌即使在无转移的情况下,也兼具成釉细胞瘤的组织学特征和细胞学异型性。据报道,该病变可起源于牙源性囊肿或成釉细胞瘤。大多数为原发性,其余则是成釉细胞瘤的恶性转化。