Department of Obstetrics and Gynecology, University of California Davis, Sacramento, California 95817, USA.
Fertil Steril. 2012 Jan;97(1):7-12. doi: 10.1016/j.fertnstert.2011.11.023.
PRO--PCOS is associated with low-grade systemic inflammation as evidenced by elevation of multiple markers of inflammation such as C-reactive protein, interleukin-18, monocyte chemoattractant protein-1 and white blood cell count as well as endothelial dysfunction and increased oxidative stress. CON--Current studies examining the evidence for low grade inflammation in PCOS are small, heterogeneous for the diagnosis, confounded by degree of adiposity and do not consistently demonstrate a clinically relevant increase in the above mentioned biomarkers.
PRO--多囊卵巢综合征（PCOS）与低度全身炎症相关，这可通过多种炎症标志物的升高来证明，如 C 反应蛋白、白细胞介素 18、单核细胞趋化蛋白-1 和白细胞计数，以及内皮功能障碍和氧化应激增加。CON--目前研究检查 PCOS 低度炎症的证据规模较小，诊断存在异质性，受肥胖程度混杂影响，并且不能始终证明上述生物标志物有临床相关的增加。
