Miller David S, Weiser Glen C, Aune Keith, Roeder Brent, Atkinson Mark, Anderson Neil, Roffe Thomas J, Keating Kim A, Chapman Phillip L, Kimberling Cleon, Rhyan Jack, Clarke P Ryan
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Vet Med Int. 2011;2011:162520. doi: 10.4061/2011/162520. Epub 2011 Nov 16.
Transmission of infectious agents from livestock reservoirs has been hypothesized to cause respiratory disease outbreaks in bighorn sheep (Ovis canadensis), and land management policies intended to limit this transmission have proven controversial. This cross-sectional study compares the infectious agents present in multiple populations of bighorn sheep near to and distant from their interface with domestic sheep (O. aries) and domestic goat (Capra hircus) and provides critical baseline information needed for interpretations of cross-species transmission risks. Bighorn sheep and livestock shared exposure to Pasteurellaceae, viral, and endoparasite agents. In contrast, although the impact is uncertain, Mycoplasma sp. was isolated from livestock but not bighorn sheep. These results may be the result of historic cross-species transmission of agents that has resulted in a mosaic of endemic and exotic agents. Future work using longitudinal and multiple population comparisons is needed to rigorously establish the risk of outbreaks from cross-species transmission of infectious agents.
有假设认为,家畜宿主传播的传染源会导致大角羊(加拿大盘羊)爆发呼吸道疾病,而旨在限制这种传播的土地管理政策已引发争议。这项横断面研究比较了多个大角羊种群中存在的传染源,这些种群与家羊(绵羊)和家山羊(山羊)的接触程度不同,为解释跨物种传播风险提供了关键的基线信息。大角羊和家畜共同暴露于巴氏杆菌科、病毒和体内寄生虫病原体。相比之下,虽然影响尚不确定,但支原体属是从家畜而非大角羊中分离出来的。这些结果可能是病原体历史性跨物种传播导致地方性病原体和外来病原体混合出现的结果。未来需要开展纵向研究和多群体比较,以严格确定传染病原体跨物种传播引发疫情的风险。