Satria Melissa N, Pacheco-Rodriguez Gustavo, Moss Joel
Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892-1590, USA.
Lymphat Res Biol. 2011;9(4):191-3. doi: 10.1089/lrb.2011.0023.
Lymphangiomatosis is a rare disease characterized by diffuse infiltration of lymphangiomas in the lung, bone, and other tissues. Due to its rarity, the spectrum of lymphangiomatosis is beginning to be elucidated based on case reports. The limited pathological, radiological, and clinical studies have shed light on this disease. Treatments have been tested in unblinded manner with promising results; however, further understanding of the pathogenesis of disease, as well as its natural history, is needed to facilitate drug development.
淋巴管瘤病是一种罕见疾病，其特征为淋巴管瘤在肺、骨骼及其他组织中弥漫性浸润。由于其罕见性，基于病例报告，淋巴管瘤病的范围才开始得以阐明。有限的病理学、放射学及临床研究已让人们对这种疾病有所了解。治疗方法已在非盲法试验中进行了测试，结果令人鼓舞；然而，为推动药物研发，仍需要进一步了解该疾病的发病机制及其自然病程。
