Monell Chemical Senses Center, 3500 Market St., Philadelphia, PA 19104, USA.
J Neurosci Methods. 2012 Mar 30;205(1):10-6. doi: 10.1016/j.jneumeth.2011.12.004. Epub 2011 Dec 17.
Most existing olfactory identification (ID) tests have the primary aim of diagnosing clinical olfactory dysfunction, thereby rendering them sub-optimal for experimental settings where the aim is to detect differences in healthy subjects' odor ID abilities.
We have developed an extended version of the olfactory ID subtest of the Sniffin' Sticks test battery to better assess the variability in ID scores and thereby olfactory abilities of healthy, adult individuals. Twenty-four odorants, corresponding cue labels, and distractor labels were added to the existing 16-item Sniffin' Sticks ID test to create the 40-item Monell Extended Sniffin' Sticks Identification Test (MONEX-40). The MONEX-40 was administered to 259 healthy young subjects, of which 72 were retested on an average of 212 days (SD 112 days) later.
The added odor items demonstrated good validity, as shown by a significant correlation of the results with the original 16-item ID test. In addition, the MONEX-40 achieved a significant test-retest and split-half reliability.
Taken together, these results suggest that the MONEX-40 is a reliable method for experimental assessment of odor ID ability in healthy, young individuals. Moreover, its use of a wider range of odors allows the experimenter to present subsets of the MONEX-40 within the same experiment while maintaining statistical power.
大多数现有的嗅觉识别 (ID) 测试主要目的是诊断临床嗅觉功能障碍,因此对于旨在检测健康受试者嗅觉识别能力差异的实验环境来说,它们并不是最优选择。
我们开发了一种 Sniffin' Sticks 测试工具包中嗅觉 ID 子测试的扩展版本,以更好地评估 ID 分数的可变性,从而评估健康成年人的嗅觉能力。我们向现有的 16 项 Sniffin' Sticks ID 测试中添加了 24 种气味剂、对应的提示标签和干扰标签,创建了 40 项 Monell 扩展 Sniffin' Sticks 识别测试 (MONEX-40)。MONEX-40 被用于 259 名健康的年轻受试者,其中 72 名受试者在平均 212 天(SD 112 天)后进行了重新测试。
添加的气味项目表现出良好的有效性,这表现在结果与原始的 16 项 ID 测试之间存在显著相关性。此外,MONEX-40 还实现了显著的测试重测和半分可靠性。
综上所述,这些结果表明,MONEX-40 是一种可靠的方法,可用于在健康的年轻个体中实验评估嗅觉识别能力。此外,它使用了更广泛的气味范围,允许实验者在同一实验中呈现 MONEX-40 的子集,同时保持统计能力。