Rotterdam Neurorehabilitation Research, Rijndam Rehabilitation Centre, Rotterdam, the Netherlands.
Arch Phys Med Rehabil. 2012 Jan;93(1 Suppl):S46-52. doi: 10.1016/j.apmr.2011.05.029.
This article describes the state of the art of Melodic Intonation Therapy (MIT), a structured aphasia therapy program using the melodic aspects of language (intonation, rhythm, and stress) to improve language production. MIT was developed in the 1970s and is still used worldwide. Nevertheless, we argue that many questions crucial for the clinical application of MIT are still unanswered. First, a review of MIT effect studies is presented showing that evidence from well-designed group studies is still lacking. It is also unclear which aspects of MIT contribute most to its therapeutic effect and which underlying neural mechanisms are involved. Two cases are presented illustrating unsolved questions concerning MIT in clinical practice, such as candidacy and the best timing of this therapy.
本文介绍了旋律语调疗法（MIT）的最新技术，这是一种使用语言的旋律方面（语调、节奏和重音）来改善语言产生的结构性失语症治疗方案。MIT 于 20 世纪 70 年代开发，至今仍在全球范围内使用。然而，我们认为，许多对 MIT 临床应用至关重要的问题仍未得到解答。首先，本文回顾了 MIT 效应研究，结果表明，仍缺乏精心设计的组研究证据。MIT 对治疗效果的贡献最大的方面以及涉及的潜在神经机制也尚不清楚。本文通过两个案例说明了在临床实践中与 MIT 相关的未解决问题，例如候选者和这种疗法的最佳时机。
