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嗜麦芽窄食单胞菌(假单胞菌)对新型抗菌药物的体外敏感性

In vitro susceptibility of Xanthomonas (Pseudomonas) maltophilia to newer antimicrobial agents.

作者信息

Khardori N, Reuben A, Rosenbaum B, Rolston K, Bodey G P

机构信息

Department of Medical Specialties, University of Texas M. D. Anderson Cancer Center, Houston 77030.

出版信息

Antimicrob Agents Chemother. 1990 Aug;34(8):1609-10. doi: 10.1128/AAC.34.8.1609.

DOI:10.1128/AAC.34.8.1609
PMID:2221872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC171884/
Abstract

The susceptibilities of 45 clinical and 3 environmental isolates of Xanthomonas maltophilia to 14 antimicrobial agents was determined by broth microdilution. The newer quinolones PD117596, PD117558, PD127391, A-56620, amifloxacin, and fleroxacin were the most active agents tested, with 70 to 99% of isolates being susceptible to these agents. All isolates were resistant to trospectomycin. The new aminoglycosides SCH24120 and SCH22591 were active against 12 and 1% of isolates, respectively.

摘要

采用肉汤微量稀释法测定了45株嗜麦芽窄食单胞菌临床分离株和3株环境分离株对14种抗菌药物的敏感性。新型喹诺酮类药物PD117596、PD117558、PD127391、A - 56620、阿米氟沙星和氟罗沙星是所测试的活性最强的药物,70%至99%的分离株对这些药物敏感。所有分离株对曲古霉素耐药。新型氨基糖苷类药物SCH24120和SCH22591分别对12%和1%的分离株有活性。

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