Kovacević Damir, Mance Tea Caljkusić, Markusić Vedran
Department of Ophthalmology, Rijeka University Hospital Center, Rijeka, Croatia.
Coll Antropol. 2011 Sep;35 Suppl 2:191-3.
The aim of this study is to evaluate vital dyes "Brilliant Blue G" (BBG) and "Membrane Blue Dual" (MBD) for intraoperative staining of the inner limiting membrane (ILM) during vitrectomy for macular hole (MH). Retrospective, comparative case series on 18 eyes with macular holes who underwent "23 and 25 gauge" pars plana vitrectomy. Main outcome measurements were staining intensity and characteristics, visual acuity, visual field, OCT measurements and complications over a period of 6 months. With the help of BBG and MBD successfully was removed complete ILM in 14 eyes. Postoperative visual acuity was improved in 12 patients, unchanged in 2 patients and worse in 4 patients. Central retinal thickness showed significant postoperative reduction with closure of macular hole. OCT values range were from -10 to -250 microm. No visual field defects and no adverse effects were found. BBG and MBD successfully identificate internal limiting membrane during vitrectomy for MH. Good anatomical and functional results are achieved with the use of both vital dyes.
本研究的目的是评估活性染料“亮蓝G”（BBG）和“膜蓝双染剂”（MBD）在黄斑裂孔（MH）玻璃体切除术期间对内界膜（ILM）进行术中染色的效果。对18例接受“23G和25G”扁平部玻璃体切除术的黄斑裂孔患者进行回顾性、对比病例系列研究。主要观察指标为6个月内的染色强度和特征、视力、视野、光学相干断层扫描（OCT）测量结果及并发症。借助BBG和MBD，14只眼中成功完全切除了ILM。12例患者术后视力提高，2例患者视力不变，4例患者视力下降。黄斑裂孔闭合后，视网膜中央厚度术后显著降低。OCT值范围为-10至-250微米。未发现视野缺损和不良反应。在MH玻璃体切除术中，BBG和MBD成功识别了内界膜。使用这两种活性染料均取得了良好的解剖学和功能结果。
