Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
Adv Mater. 2012 Jan 24;24(4):492-6. doi: 10.1002/adma.201103794. Epub 2011 Dec 27.
Spray layer-by-layer assembly is used to create hemostatic films containing thrombin and tannic acid. The spray assembly technique enables coating of porous and absorbent commercial gelatin sponges with these films. Coated sponges are able to promote instantaneous hemostasis in a porcine spleen bleeding model.
喷雾层层组装用于创建含有凝血酶和鞣酸的止血薄膜。喷雾组装技术可将这些薄膜涂覆在多孔和吸水的商业明胶海绵上。涂覆的海绵能够在猪脾脏出血模型中促进即时止血。