School of Health and Sport Sciences, Faculty of Science, Health & Education, University of the Sunshine Coast, Queensland 4556, Australia.
Steroids. 2012 Apr;77(5):413-8. doi: 10.1016/j.steroids.2011.12.022. Epub 2012 Jan 10.
The hormonal response of 32 older men (70-80years) to a bout of sub-maximum aerobic exercise was examined before, after 16weeks of resistance or aerobic training and again after 4weeks of detraining. Blood samples were obtained at rest and immediately post sub-maximum exercise (30min @ 70% VO(2) max) to determine the concentrations of growth hormone (GH), insulin-like growth factor-1 (IGF-1), testosterone (Test), sex hormone-binding globulin (SHBG) and the calculation of free testosterone (FT). Both training groups had significant increases in leg strength and VO(2) max after 16weeks training but leg strength and VO(2) max returned to pre-training levels in the aerobic training and resistance training groups, respectively. During the 20week study there was no change in resting concentrations of any hormones among the three groups. There was no increase in GH, IGF-1 or SHBG immediately post sub-maximum exercise in any of the groups before training, after 16weeks training or after 4weeks detraining. Testosterone and FT increased immediately post sub-maximum exercise within all groups before training, after 16weeks training and after 4weeks detraining with the increase in Test and FT higher after 16weeks of resistance training compared to before training and after 4weeks detraining within the resistance training group. The increased responsiveness of Test and FT after 16weeks of resistance training was lost after 4weeks of detraining. Our results indicate that some physiological and hormonal adaptations gained after 16weeks training are lost after only 4weeks detraining.
32 名老年男性（70-80 岁）在进行一次亚最大有氧运动前、16 周抗阻或有氧训练后以及 4 周停训后，其激素反应均被检测。在休息时和亚最大运动后即刻（30min@70%最大摄氧量）采集血样，以测定生长激素（GH）、胰岛素样生长因子-1（IGF-1）、睾酮（Test）、性激素结合球蛋白（SHBG）浓度，并计算游离睾酮（FT）。两组训练后腿部力量和最大摄氧量（VO2max）均显著增加，但有氧训练组和抗阻训练组腿部力量和 VO2max 在停训后均恢复至训练前水平。在 20 周的研究中，三组的静息激素浓度均无变化。在训练前、16 周训练后和 4 周停训后，任何一组亚最大运动后 GH、IGF-1 或 SHBG 均无增加。在训练前、16 周训练后和 4 周停训后，所有组在亚最大运动后 Test 和 FT 即刻增加，且抗阻训练组在 16 周抗阻训练后和 4 周停训后的 Test 和 FT 增加高于训练前和 4 周停训后。抗阻训练 16 周后，Test 和 FT 的反应性增加在 4 周停训后消失。我们的结果表明，16 周训练后获得的一些生理和激素适应性在仅 4 周停训后就会丧失。
