Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Immunology. 2012 May;136(1):28-9. doi: 10.1111/j.1365-2567.2012.03555.x.
As a commentary on a recently published paper in Immunology, this article summaries the principle of norovirus P particle as a promising vaccine against noroviruses. It emphasizes the importance of P particle formation in the immune enhancement of the vaccine and methods for production/verification of high quality P particles which may be easily neglected by researchers.
作为对最近发表在《免疫学》杂志上的一篇论文的评论,本文总结了诺如病毒 P 粒子作为一种有前途的诺如病毒疫苗的原理。它强调了 P 粒子形成在疫苗免疫增强中的重要性,以及生产/验证高质量 P 粒子的方法,这些方法很容易被研究人员忽视。