Turnbull Catherine, Osborn David A
Department ofHealth, South Australia, Adelaide, Australia.
Cochrane Database Syst Rev. 2012 Jan 18;1(1):CD004456. doi: 10.1002/14651858.CD004456.pub3.
One potential method of improving outcome for pregnant or postpartum women with a drug or alcohol problem is with home visits.
To determine the effects of home visits during pregnancy and/or after birth for women with a drug or alcohol problem.
We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (30 November 2011), CENTRAL (The Cochrane Library 2011, Issue 4 of 4), MEDLINE (1966 to 30 November 2011), EMBASE (1980 to 30 November 2011), CINAHL (1982 to 30 November 2011) and PsycINFO (1974 to 30 November 2011) supplemented by searches of citations from previous reviews and trials and contact with experts.
Studies using random or quasi-random allocation of pregnant or postpartum women with a drug or alcohol problem to home visits. Trials enrolling high-risk women of whom more than 50% were reported to use drugs or alcohol were also eligible.
Review authors performed assessments of trials independently. We performed statistical analyses using fixed-effect and random-effects models where appropriate.
Seven studies (reporting 803 mother-infant pairs) compared home visits mostly after birth with no home visits. Visitors included community health nurses, paediatric nurses, trained counsellors, paraprofessional advocates, midwives and lay African-American women. Several studies had significant methodological limitations. There was no significant difference in continued illicit drug use (three studies, 384 women; risk ratio (RR) 1.05, 95% confidence interval (CI) 0.89 to 1.24), continued alcohol use (three studies, 379 women; RR 1.18, 95% CI 0.96 to 1.46), failure to enrol in a drug treatment program (two studies, 211 women; RR 0.45, 95% CI 0.10 to 1.94), not breastfeeding at six months (two studies, 260 infants; RR 0.95, 95% CI 0.83 to 1.10), incomplete six-month infant vaccination schedule (two studies, 260 infants; RR 1.09, 95% CI 0.91 to 1.32), the Bayley Mental Development Index (three studies, 199 infants; mean difference 2.89, 95% CI -1.17 to 6.95) or Psychomotor Index (MD 3.14, 95% CI -0.03 to 6.32), child behavioural problems (RR 0.46, 95% CI 0.21 to 1.01), infants not in care of biological mother (two studies, 254 infants; RR 0.83, 95% CI 0.50 to 1.39), non-accidental injury and non-voluntary foster care (two studies, 254 infants; RR 0.16, 95% CI 0.02 to 1.23) or infant death (three studies, 288 infants; RR 0.70, 95% CI 0.12 to 4.16). Individual studies reported a significant reduction in involvement with child protective services (RR 0.38, 95% CI 0.20 to 0.74) and failure to use postpartum contraception (RR 0.41, 95% CI 0.20 to 0.82).
AUTHORS' CONCLUSIONS: There is insufficient evidence to recommend the routine use of home visits for pregnant or postpartum women with a drug or alcohol problem. Further large, high-quality trials are needed.
对于有药物或酒精问题的孕妇或产后妇女,一种可能改善结局的方法是进行家访。
确定孕期和/或产后家访对有药物或酒精问题妇女的影响。
我们检索了Cochrane妊娠与分娩组试验注册库(2011年11月30日)、Cochrane系统评价数据库(《Cochrane图书馆》2011年第4期)、医学期刊数据库(1966年至2011年11月30日)、荷兰医学文摘数据库(1980年至2011年11月30日)、护理学与健康领域数据库(1982年至2011年11月30日)以及心理学文摘数据库(1974年至2011年11月30日),并补充检索了以往综述和试验的参考文献以及与专家联系获取的信息。
采用随机或半随机分配方法,将有药物或酒精问题的孕妇或产后妇女分配到家访组的研究。纳入高危妇女且报告使用药物或酒精的比例超过50%的试验也符合条件。
综述作者独立对试验进行评估。我们在适当情况下使用固定效应和随机效应模型进行统计分析。
七项研究(报告了803对母婴)比较了大多在产后进行家访与不进行家访的情况。家访人员包括社区健康护士、儿科护士、经过培训的咨询师、准专业倡导者、助产士和非专业的非裔美国女性。几项研究存在显著的方法学局限性。在持续非法药物使用方面(三项研究,384名妇女;风险比(RR)为1.05,95%置信区间(CI)为0.89至1.24)、持续酒精使用方面(三项研究,379名妇女;RR为1.18,95%CI为0.96至1.46)、未参加药物治疗项目方面(两项研究,211名妇女;RR为0.45,95%CI为0.10至1.94)、六个月时未进行母乳喂养方面(两项研究,260名婴儿;RR为0.95,95%CI为0.83至1.10)、六个月婴儿疫苗接种计划未完成方面(两项研究,260名婴儿;RR为1.09,95%CI为0.91至1.32)、贝利智力发育指数(三项研究,199名婴儿;平均差为2.89,95%CI为-1.17至6.95)或精神运动指数(平均差为3.14,95%CI为-0.03至6.32)、儿童行为问题方面(RR为0.46,95%CI为0.21至1.01)、婴儿未由亲生母亲照料方面(两项研究,254名婴儿;RR为0.83,95%CI为0.50至1.39)、非意外伤害和非自愿寄养方面(两项研究,254名婴儿;RR为0.16,95%CI为0.02至1.23)或婴儿死亡方面(三项研究,288名婴儿;RR为0.70,95%CI为0.12至4.16)无显著差异。个别研究报告称,参与儿童保护服务的情况显著减少(RR为0.38,95%CI为0.20至0.74)以及未使用产后避孕措施的情况显著减少(RR为0.41,95%CI为0.20至0.82)。
没有足够证据推荐对有药物或酒精问题的孕妇或产后妇女常规进行家访。需要进一步开展大规模、高质量的试验。