Institute of Gerontology and Geriatrics, Department of Human and Education Science, University of Perugia, Perugia, Italy.
Dement Geriatr Cogn Disord. 2011;32(5):301-7. doi: 10.1159/000334657. Epub 2012 Jan 19.
The main aims of the study were the translation and the subsequent validation in Italian of the Addenbrooke's Cognitive Examination Revised (ACE-R), and the evaluation of its usefulness in discriminating cognitively normal subjects from patients with mild dementia in an elderly population.
The ACE-R was translated and adapted into Italian. The Italian ACE-R was administered to a group of 179 elderly subjects (72 cognitively healthy and 107 subjects with mild dementia, mean age 75.4±6.4 years). The group was stratified into two subsamples according to age, i.e. a young-old (<75 years) and an old-old (≥75 years) group, in order to evaluate the sensitivity and specificity of the test in detecting dementia in different age strata of elderly subjects.
The reliability of the Italian ACE-R was extremely good (α-coefficient=0.85). Two different cutoffs were identified for young-old (cutoff 79; sensitivity 90% and specificity 80%) and old-old subjects (cutoff 60; sensitivity 82% and specificity 100%).
The Italian ACE-R is a valid screening tool to detect dementia, especially in the old-old population, which represents not only the fastest growing age group but also the group at the highest risk of dementia in Western countries.
本研究的主要目的是将 Addenbrooke 认知测验修订版（ACE-R）翻译成意大利语，并对其在区分认知正常的老年人和轻度痴呆患者方面的有效性进行评估。
ACE-R 被翻译成并适应为意大利语。对 179 名老年人进行了意大利语 ACE-R 测试（72 名认知正常，107 名轻度痴呆，平均年龄 75.4±6.4 岁）。该组根据年龄分为两个亚组，即年轻老年人（<75 岁）和老年老年人（≥75 岁），以评估该测试在检测不同年龄组老年人痴呆方面的敏感性和特异性。
意大利语 ACE-R 的可靠性非常好（α系数=0.85）。为年轻老年人（截断值 79；敏感性 90%，特异性 80%）和老年老年人（截断值 60；敏感性 82%，特异性 100%）确定了两个不同的截断值。
意大利语 ACE-R 是一种有效的筛查工具，可用于检测痴呆症，特别是在老年人群中，这不仅是增长最快的年龄组，也是西方国家痴呆症风险最高的人群。
