Tagawa M, Omata M, Marion P L
First Department of Medicine, Chiba University School of Medicine, Japan.
Gastroenterol Jpn. 1990 Sep;25 Suppl 2:20-2. doi: 10.1007/BF02779923.
Hepadnaviruses have open reading frames of surface, core, polymerase and X protein on the minus strand of the genome. We analyzed a plus strand of duck hepatitis B virus (DHBV) for the presence of open reading frame with a computer program. We found one frame on the area that is complement to 3' end of polymerase gene and 5' end of precore gene. That open reading frame is conserved in three strains of DHBV, and the predicted protein is about 80 amino acids.