Department of Pharmacology, University of Alcalá, Alcalá de Henares, and Dermatology Service, Hospital Ramon y Cajal, Madrid, Spain.
Food Chem Toxicol. 2012 Mar;50(3-4):1109-17. doi: 10.1016/j.fct.2012.01.004. Epub 2012 Jan 18.
The photoprotective potential against UVB radiation of extracts obtained from 21 commercial macroalgae from the Phyla Ochrophyta and Rhodophyta, was evaluated in vivo, using the zebrafish embryo as a whole model organism. Our results showed that the phenolic extracts from Macrocystis pyrifera and Porphyra columbina exhibited the highest photoprotective activity, close to complete photoprotection (100%), similar to that obtained for the carrageenophytes Sarcothalia radula and Gigartina skottsbergii. Under the assayed conditions, the extracts were safe and non-toxic to the embryos at a concentration of 0.04 mg/ml PGE.
利用斑马鱼胚胎整体模型，对来自 Ochrophyta 和 Rhodophyta 门的 21 种商业大型藻类的提取物的抗 UVB 辐射的光保护潜力进行了体内评估。我们的结果表明，来自巨藻和紫菜的酚类提取物表现出最高的光保护活性，接近完全光保护（100%），类似于卡拉胶藻 Sarcothalia radula 和 Gigartina skottsbergii 的光保护活性。在所测试的条件下，提取物在 0.04mg/ml PGE 浓度下对胚胎安全且无毒。
