Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
Am J Clin Nutr. 2012 Mar;95(3):732-9. doi: 10.3945/ajcn.111.023200. Epub 2012 Jan 25.
Previous studies have reported that green tea consumption is associated with a lower risk of diseases that cause functional disability, such as stroke, cognitive impairment, and osteoporosis. Although it is expected that green tea consumption would lower the risk of incident functional disability, this has never been investigated directly.
The objective was to determine the association between green tea consumption and incident functional disability in elderly individuals.
We conducted a prospective cohort study in 13,988 Japanese individuals aged ≥65 y. Information on daily green tea consumption and other lifestyle factors was collected via questionnaire in 2006. Data on functional disability were retrieved from the public Long-term Care Insurance database, in which subjects were followed up for 3 y. We used Cox proportional hazards regression analysis to investigate the association between green tea consumption and functional disability.
The 3-y incidence of functional disability was 9.4% (1316 cases). The multiple-adjusted HR (95% CI) of incident functional disability was 0.90 (0.77, 1.06) among respondents who consumed 1-2 cups green tea/d, 0.75 (0.64, 0.88) for those who consumed 3-4 cups/d, and 0.67 (0.57, 0.79) for those who consumed ≥5 cups/d in comparison with those who consumed <1 cup/d (P-trend < 0.001).
Green tea consumption is significantly associated with a lower risk of incident functional disability, even after adjustment for possible confounding factors.
先前的研究报告称，绿茶的摄入与某些疾病的风险降低相关，这些疾病会导致功能障碍，如中风、认知障碍和骨质疏松症。虽然预计绿茶的摄入会降低发生功能障碍的风险，但这一点从未被直接研究过。
本研究旨在确定绿茶摄入与老年人发生功能障碍之间的关联。
我们对 13988 名年龄≥65 岁的日本个体进行了一项前瞻性队列研究。在 2006 年通过问卷收集了每日绿茶摄入和其他生活方式因素的信息。通过公共长期护理保险数据库获取了有关功能障碍的数据，在该数据库中，对受试者进行了 3 年的随访。我们使用 Cox 比例风险回归分析来研究绿茶摄入与功能障碍之间的关联。
3 年的功能障碍发生率为 9.4%（1316 例）。多因素调整后的 HR（95%CI）为，与每天摄入<1 杯绿茶的人相比，每天摄入 1-2 杯、3-4 杯和≥5 杯绿茶的人发生功能障碍的风险分别为 0.90（0.77，1.06）、0.75（0.64，0.88）和 0.67（0.57，0.79）（趋势 P<0.001）。
即使在调整了可能的混杂因素后，绿茶的摄入与发生功能障碍的风险降低显著相关。
