D'Angelo L J, Hierholzer J C, Keenlyside R A, Anderson L J, Martone W J
J Infect Dis. 1979 Jul;140(1):42-7. doi: 10.1093/infdis/140.1.42.
During the summer of 1977, an outbreak of pharyngoconjunctival fever (PCF) occurred at a private recreational facility in Georgia. A total of 72 cases of PCF was identified. Adenovirus type 4 (AV-4) was recovered from conjunctival or pharyngeal swab specimens from 20 of 26 persons in the group of cases tested. AV-4 was also recovered, for the first time reported in the literature, from two concentrated samples of water obtained from the swimming pool at the facility on different dates. All persons affected had had direct or indirect contact with the pool. A linear relation between the amount of time spent in the water and the attack rate was demonstrated (r = 0.929, P less than 0.01). Investigation showed that inadequate amounts of chlorine had been added to the pool water. Frequently, levels of free chlorine were below the recommended level of 0.4 mg/liter. Breakpoint chlorination and closing of the pool for the summer stopped the spread of PCF.
1977年夏天，佐治亚州的一个私人娱乐设施发生了咽结膜热（PCF）疫情。共确诊72例PCF病例。在检测的26例病例组中，从20人的结膜或咽拭子标本中分离出4型腺病毒（AV-4）。文献首次报道，还从该设施游泳池不同日期采集的两份浓缩水样中分离出AV-4。所有感染者均直接或间接接触过该泳池。结果表明，在水中停留的时间与发病率之间存在线性关系（r = 0.929，P < 0.01）。调查显示，泳池水中添加的氯量不足。游离氯水平经常低于推荐的0.4毫克/升水平。采用折点氯化法并在夏季关闭泳池后，PCF疫情得到控制。
