Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan.
Neuroimage. 2012 Aug 15;62(2):699-705. doi: 10.1016/j.neuroimage.2012.01.072. Epub 2012 Jan 21.
Inverse imaging (InI) supercharges the sampling rate of traditional functional MRI 10-100 fold at a cost of a moderate reduction in spatial resolution. The technique is inspired by similarities between multi-sensor magnetoencephalography (MEG) and highly parallel radio-frequency (RF) MRI detector arrays. Using presently available 32-channel head coils at 3T, InI can be sampled at 10 Hz and provides about 5-mm cortical spatial resolution with whole-brain coverage. Here we discuss the present applications of InI, as well as potential future challenges and opportunities in further improving its spatiotemporal resolution and sensitivity. InI may become a helpful tool for clinicians and neuroscientists for revealing the complex dynamics of brain functions during task-related and resting states.
逆像(InI)以适度降低空间分辨率为代价,将传统功能磁共振成像(fMRI)的采样率提高了 10-100 倍。该技术的灵感来自多传感器脑磁图(MEG)和高并行射频(RF)MRI 探测器阵列之间的相似性。在 3T 下使用目前可用的 32 通道头部线圈,InI 可以以 10Hz 的频率进行采样,并提供约 5mm 的皮质空间分辨率和全脑覆盖。在这里,我们讨论了 InI 的当前应用,以及在进一步提高其时空分辨率和灵敏度方面的潜在未来挑战和机遇。InI 可能成为临床医生和神经科学家的有用工具,用于揭示任务相关和静息状态下大脑功能的复杂动态。