Chan Mf, Yang J, Song Y, Burman C, Chan P, Li S
Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Biomed Imaging Interv J. 2011 Apr;7(2):e11. doi: 10.2349/biij.7.2.e11. Epub 2011 Apr 1.
The imaging characteristics of two popular kV cone-beam CT (CBCT) and two MVCT systems utilised in image-guided radiation therapy (IGRT) were evaluated.
The study was performed on Varian Clinac iX, Elekta Synergy S, Siemens Oncor, and Tomotherapy. A CT phantom (Catphan-504, Phantom Laboratory, Salem, NY) was scanned for measurements of image quality including image noise, uniformity, density accuracy, spatial resolution, contrast linearity, and contrast resolution. The measurement results were analysed using in-house image analysis software. Reproducibility, position correction, and geometric accuracy were also evaluated with markers in a smaller alignment phantom. The performance evaluation compared volumetric image properties from these four systems with those from a conventional diagnostic CT (CCT).
It was shown that the linearity of the two kV CBCT was fairly consistent with CCT. The Elekta CBCT with half-circle 27-cm FOV had higher CT numbers than the other three systems. The image noises of the Elekta kV CBCT, Siemens MV CBCT, and Tomotherapy fan-beam CT (FBCT) are about 2-4 times higher than that of the Varian CBCT. The spatial resolutions of two kV CBCTs and two MV CBCTs were 8-11 lp/cm and 3-5 lp/cm, respectively.
Elekta CBCT provided a faster image reconstruction and low dose per scan for half-circle scanning. Varian CBCT had relatively lower image noise. Tomotherapy FBCT had the best uniformity.
评估在图像引导放射治疗(IGRT)中使用的两种常用千伏锥形束CT(CBCT)和两种兆伏CT(MVCT)系统的成像特性。
该研究在瓦里安Clinac iX、医科达Synergy S、西门子Oncor和螺旋断层放疗系统上进行。使用CT体模(Catphan - 504,幻影实验室,纽约州塞勒姆)进行扫描,以测量图像质量,包括图像噪声、均匀性、密度准确性、空间分辨率、对比度线性和对比度分辨率。测量结果使用内部图像分析软件进行分析。还使用较小的校准体模中的标记物评估了再现性、位置校正和几何准确性。性能评估将这四个系统的容积图像特性与传统诊断CT(CCT)的特性进行了比较。
结果表明,两种千伏CBCT的线性与CCT相当一致。具有27厘米半圈视野的医科达CBCT的CT值高于其他三个系统。医科达千伏CBCT、西门子兆伏CBCT和螺旋断层放疗系统扇形束CT(FBCT)的图像噪声比瓦里安CBCT高约2 - 4倍。两种千伏CBCT和两种兆伏CBCT的空间分辨率分别为8 - 11线对/厘米和3 - 5线对/厘米。
医科达CBCT提供了更快的图像重建速度,并且半圈扫描的每次扫描剂量较低。瓦里安CBCT的图像噪声相对较低。螺旋断层放疗系统FBCT的均匀性最佳。