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对单个学区抽动秽语综合征的一项流行病学研究。

An epidemiologic study of Tourette's syndrome in a single school district.

作者信息

Comings D E, Himes J A, Comings B G

机构信息

Department of Medical Genetics, City of Hope National Medical Center, Duarte, Calif. 91010.

出版信息

J Clin Psychiatry. 1990 Nov;51(11):463-9.

PMID:2228981
Abstract

To evaluate the frequency of Gilles de la Tourette's syndrome (TS) in children, 3034 students in three schools in a single school district in greater Los Angeles were monitored frequently over a 2-year period by a school psychologist thoroughly familiar with the symptoms of the disorder. A portion of the cases were also evaluated in a TS clinic. A total of 14 males fulfilled the Tourette Syndrome Association research criteria for definite TS. When corrected for the number of students in special education classes in the monitored schools, the frequency of definite TS in males was 1 in 152. An additional 7 males who differed only in that they were not observed for a full year were termed definite TS less than 1 year. When the two groups were combined, the frequency of definite TS was 1 in 95 for males and 1 in 759 for females. These figures do not include an additional 10 males diagnosed as having definite transient tic disorder, 2 males diagnosed as having probable TS, and 10 males diagnosed as having possible TS. In addition to tics, most of these children had problems with attention span, obsessive compulsive behavior, and learning and/or conduct disorders. Seventy percent of the students with definite TS or definite TS less than 1 year were in special education classes. Twelve percent of the children in special education classes had definite TS or definite TS less than 1 year, and 28% were in one of the diagnostic categories of definite, probable, or possible. All of the 10 definite TS patients that were seen in the clinic had attention-deficit hyperactivity disorder.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为评估儿童抽动秽语综合征(TS)的发病率,在大洛杉矶地区一个学区的三所学校中,由一位熟知该疾病症状的学校心理学家在两年时间里对3034名学生进行了频繁监测。部分病例还在抽动秽语综合征诊所进行了评估。共有14名男性符合抽动秽语综合征协会明确TS的研究标准。经监测学校中特殊教育班级学生人数校正后,男性中明确TS的发病率为1/152。另有7名男性仅因未被观察满一年而被称为确诊时间不足一年的TS患者。将两组合并后,男性中明确TS的发病率为1/95,女性为1/759。这些数字不包括另外10名被诊断为明确短暂性抽动障碍的男性、2名被诊断为可能患有TS的男性以及10名被诊断为可能患有TS的男性。除了抽动症状外,这些孩子中的大多数还存在注意力不集中、强迫行为以及学习和/或行为障碍问题。确诊TS或确诊时间不足一年的TS患者中有70%在特殊教育班级。特殊教育班级中有12%的儿童确诊为TS或确诊时间不足一年的TS患者,28%属于明确、可能或可能患有TS的诊断类别之一。在诊所就诊的10名明确TS患者均患有注意力缺陷多动障碍。(摘要截选至250词)

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