伤寒热诊断方法的比较。
Comparison of methods for the diagnosis of typhoid fever.
作者信息
Duthie R, French G L
机构信息
Department of Microbiology, Prince of Wales Hospital, Shatin, New Territories, Hong Kong.
出版信息
J Clin Pathol. 1990 Oct;43(10):863-5. doi: 10.1136/jcp.43.10.863.
Abstract
Over five years the Bactec radiometric blood culture method yielded Salmonella typhi in 41 of 45 confirmed cases of typhoid fever, 90% of which were from the first culture set taken. Blood clot culture was positive in 18 (41%) of 44 confirmed cases and stool culture in 24 (59%) of 41. The yield from 2189 Widal clot cultures was only 0.03%. There were 68 positive results in 2258 unpaired Widal tests: 23 of them were falsely positive and 13 falsely negative, but in 11 out of 68 cases the Widal was the only positive laboratory test. It is concluded that routine clot culture is not cost effective if a sensitive blood culture method is used, and that the Widal test is useful only in selected patients.
摘要
在五年时间里，Bactec放射性血液培养法在45例确诊伤寒热病例中的41例检测出伤寒杆菌，其中90%的阳性结果来自首次采集的培养样本。44例确诊病例中有18例（41%）血凝块培养呈阳性，41例中有24例（59%）粪便培养呈阳性。2189次肥达氏凝集试验血凝块培养的阳性率仅为0.03%。2258次非配对肥达氏试验中有68次阳性结果：其中23次为假阳性，13次为假阴性，但在68例病例中有11例肥达氏试验是唯一呈阳性的实验室检测。得出的结论是，如果使用敏感的血液培养方法，常规血凝块培养不具有成本效益，并且肥达氏试验仅对部分选定患者有用。
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