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评估用于区分流感嗜血杆菌和溶血性嗜血杆菌的新型生物标志物基因。

Evaluation of new biomarker genes for differentiating Haemophilus influenzae from Haemophilus haemolyticus.

机构信息

Meningitis and Vaccine Preventable Diseases Branch, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.

出版信息

J Clin Microbiol. 2012 Apr;50(4):1422-4. doi: 10.1128/JCM.06702-11. Epub 2012 Feb 1.

DOI:10.1128/JCM.06702-11
PMID:22301020
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3318567/
Abstract

PCR detecting the protein D (hpd) and fuculose kinase (fucK) genes showed high sensitivity and specificity for identifying Haemophilus influenzae and differentiating it from H. haemolyticus. Phylogenetic analysis using the 16S rRNA gene demonstrated two distinct groups for H. influenzae and H. haemolyticus.

摘要

聚合酶链反应（PCR）检测蛋白 D（hpd）和果糖激酶（fucK）基因对鉴定流感嗜血杆菌和将其与副流感嗜血杆菌区分具有高灵敏度和特异性。使用 16S rRNA 基因进行的系统发育分析表明，流感嗜血杆菌和副流感嗜血杆菌分为两个不同的组。

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