Epidemiology Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD; Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
Epidemiology Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD; Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
Chest. 2012 Aug;142(2):432-439. doi: 10.1378/chest.11-2209.
Bronchiectasis is a potentially serious condition characterized by permanent and abnormal widening of the airways, the prevalence of which is not well described. We sought to describe the trends, associated conditions, and risk factors for bronchiectasis among adults aged ≥ 65 years.
A 5% sample of the Medicare outpatient claims database was analyzed for bronchiectasis trends among beneficiaries aged ≥ 65 years from 2000 to 2007. Bronchiectasis was identified using International Classification of Diseases, Ninth Revision, Clinical Modification claim diagnosis codes for acquired bronchiectasis. Period prevalence was used to describe sex- and race/ethnicity-specific rates, and annual prevalence was used to describe trends and age-specific rates. We estimated trends using Poisson regression and odds of bronchiectasis using multivariate logistic regression.
From 2000 to 2007, 22,296 people had at least one claim for bronchiectasis. The 8-year period prevalence of bronchiectasis was 1,106 cases per 100,000 people. Bronchiectasis increased by 8.7% per year. We identified an interaction between the number of thoracic CT scans and race/ethnicity; period prevalence varied by a greater degree by number of thoracic CT scans among Asians compared with whites or blacks. Among people with one CT scan, Asians had a 2.5- and 3.9-fold higher period prevalence compared with whites and blacks.
Bronchiectasis prevalence increased significantly from 2000 to 2007 in the Medicare outpatient setting and varied by age, sex, and race/ethnicity. This increase could be due to a true increase in the condition or an increased recognition of previously undiagnosed cases.
支气管扩张症是一种潜在的严重疾病,其特征为气道永久性和异常扩张,其流行程度尚不清楚。我们旨在描述 65 岁及以上成年人支气管扩张症的趋势、相关疾病和危险因素。
分析了 2000 年至 2007 年期间 Medicare 门诊患者数据库中 5%的支气管扩张症趋势,纳入 65 岁及以上的受益人群。使用国际疾病分类,第九修订版,临床修正版获得性支气管扩张症的诊断代码来确定支气管扩张症。应用时期患病率描述性别和种族/民族特异性发病率,应用年度患病率描述趋势和年龄特异性发病率。我们使用泊松回归估计趋势,使用多变量逻辑回归估计支气管扩张症的可能性。
2000 年至 2007 年期间,有 22296 人至少有 1 次支气管扩张症的诊断。8 年时期患病率为每 100000 人中有 1106 例。支气管扩张症每年增加 8.7%。我们发现,胸部 CT 扫描次数与种族/民族之间存在交互作用;与白种人和黑种人相比,亚洲人胸部 CT 扫描次数越多,时期患病率的差异越大。在接受过一次 CT 扫描的人群中,亚洲人比白种人和黑种人的时期患病率高 2.5 倍和 3.9 倍。
在 Medicare 门诊环境中,支气管扩张症的患病率从 2000 年到 2007 年显著增加,并且因年龄、性别和种族/民族而异。这种增加可能是由于该疾病的真实增加,也可能是由于对以前未确诊病例的认识增加。