Rose D P, Connolly J M
Division of Nutrition and Endocrinology, American Health Foundation, Valhalla, New York.
Med Oncol Tumor Pharmacother. 1990;7(2-3):121-30. doi: 10.1007/BF02988539.
A review of the epidemiological and experimental data suggests that dietary modification does have a place in breast cancer prevention. This needs to be considered at three levels: dietary recommendations for the general population, dietary intervention in the management of women at high risk for breast cancer, and the place for dietary therapy as a component of regimens intended to reduce risk of recurrence after primary treatment of breast cancer ('secondary prevention'). Based on present evidence, a dietary approach to breast cancer prevention should include weight control, when indicated, a reduction in dietary fat intake to approximately 20% of total fats, and an increase in fiber consumption to 25-30 g day-1. Further studies are indicated to determine the optimal qualitative composition of dietary fat consumed, and the nature of supplemental fiber.
对流行病学和实验数据的综述表明，饮食调整在乳腺癌预防中确实占有一席之地。这需要在三个层面加以考虑：针对普通人群的饮食建议、对乳腺癌高危女性管理中的饮食干预，以及饮食疗法作为旨在降低乳腺癌原发治疗后复发风险（“二级预防”）方案组成部分的地位。基于目前的证据，预防乳腺癌的饮食方法应包括在必要时控制体重，将膳食脂肪摄入量减少至总脂肪量的约20%，并将膳食纤维摄入量增加至每日25 - 30克。需要进一步研究以确定所摄入膳食脂肪的最佳质量组成以及补充膳食纤维的性质。
