Merz Pharmaceuticals GmbH Global R&D, Frankfurt, Germany.
Int J Audiol. 2012 Sep;51(9):671-7. doi: 10.3109/14992027.2011.653448. Epub 2012 Feb 20.
To investigate and confirm the reliability and validity of the tinnitus handicap inventory 12 (THI-12) in various countries and languages.
Prospective, observational study conducted in seven countries, using linguistically harmonized versions of the THI-12 in six languages. These were evaluated for test-retest reliability, internal consistency reliability, known-groups validity, and construct validity. Basic psychometric properties of supporting instruments were compared. Questionnaires were completed by the subjects at baseline and again after 12-30 days.
Adults with a clinical diagnosis of subjective tinnitus.
An exploratory factor analysis of the THI-12 items for the U.S. study population at baseline revealed a single common factor of high eigenvalue. Confirmatory factor analysis supported this in the separate countries. Test-retest reliability was moderate to high, and the conclusions were supported by a known-groups analysis; correlations with other scales expected to support construct validity were moderate.
The THI-12 total score showed acceptable psychometric properties for all countries tested. The relationships between the THI-12 and the one-month and one-week versions of the TRS and TSS were similar and convergent. The THI-12 is thus a promising diagnostic tool for assessing treatment effects in multi-cultural and multi-lingual trials on tinnitus therapy.
调查并确认耳鸣残疾量表 12 版（THI-12）在不同国家和语言中的信度和效度。
在七个国家进行前瞻性、观察性研究，使用六种语言的语言协调版本的 THI-12。评估其重测信度、内部一致性信度、已知组有效性和结构有效性。比较支持工具的基本心理测量特性。受试者在基线和 12-30 天后完成问卷。
有主观耳鸣临床诊断的成年人。
美国研究人群在基线时对 THI-12 项目进行的探索性因子分析显示，高特征值的单一共同因子。在单独的国家进行的验证性因子分析支持这一点。重测信度为中等到高度，并且已知组分析支持该结论；与预期支持结构有效性的其他量表的相关性为中度。
THI-12 总分在所有测试的国家都具有可接受的心理测量特性。THI-12 与 TRS 和 TSS 的一个月和一周版本之间的关系相似且一致。因此，THI-12 是评估耳鸣治疗多文化和多语言试验治疗效果的有前途的诊断工具。
