卵巢癌筛查

Ovarian cancer screening.

作者信息

van Nagell John R, Pavlik Edward John

机构信息

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Kentucky Chandler Medical Center-Markey Cancer Center, Lexington, Kentucky, USA.

出版信息

Clin Obstet Gynecol. 2012 Mar;55(1):43-51. doi: 10.1097/GRF.0b013e3182460c0d.

DOI:10.1097/GRF.0b013e3182460c0d

PMID:22343228

Abstract

Annual screening of asymptomatic postmenopausal women using a combination of transvaginal sonography and serum Ca-125 has been evaluated in 4 major clinical trials as a means to facilitate earlier detection of ovarian cancer. In several trials, screening has caused a decrease in stage at detection. These ovarian cancer screening trials are reviewed. The effect of screening on ovarian cancer mortality varies in different trials and is the subject of further investigation.

摘要

在4项主要临床试验中，对无症状绝经后妇女联合使用经阴道超声检查和血清Ca-125进行年度筛查，已被评估为一种促进卵巢癌早期检测的手段。在几项试验中，筛查已使检测时的分期降低。本文对这些卵巢癌筛查试验进行了综述。筛查对卵巢癌死亡率的影响在不同试验中有所不同，仍是进一步研究的主题。