Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Circ Res. 2012 Feb 17;110(4):526-9. doi: 10.1161/RES.0b013e31824ae5c1.
The behavior of the mitochondrial permeability transition pore has been linked to mitochondrial maturation underlying cardiomyocyte differentiation in the embryo. Mitochondrial signaling in heart development has direct implications for cardiogenesis and stem cell lineage specification.
线粒体通透性转换孔的行为与胚胎中心肌细胞分化所涉及的线粒体成熟有关。心脏发育中的线粒体信号转导对心脏发生和干细胞谱系特化有直接影响。