Department of Bioengineering, University of California at San Diego, La Jolla, California, USA.
Nat Immunol. 2012 Feb 16;13(3):199-203. doi: 10.1038/ni.2244.
System-wide measurements of gene expression by DNA microarray and, more recently, RNA-sequencing strategies have become de facto tools of modern biology and have led to deep understanding of biological mechanisms and pathways. However, analyses of the measurements have often ignored statistically robust methods that account for variance, resulting in misleading biological interpretations.
通过 DNA 微阵列和最近的 RNA 测序策略进行全系统的基因表达测量已成为现代生物学的事实上的工具，并深入了解了生物学机制和途径。然而，这些测量的分析往往忽略了统计上稳健的方法，这些方法考虑了方差，从而导致了误导性的生物学解释。
