Ahmed Syed Moied, Nadeem Abu, Islam Mohd Sabihul, Agarwal Shiwani, Singh Lalit
Department of Anesthesiology, JN Medical College, AMU, Aligarh, India.
J Anaesthesiol Clin Pharmacol. 2012 Jan;28(1):45-50. doi: 10.4103/0970-9185.92434.
Snake bites are the common cause of morbidity and mortality in tropical countries.
To analyze the outcome of snake bite victims
Retrospective analysis of data from Intensive care unit, Department of Anesthesiology.
All the patients admitted in the intensive care unit for snake bite management during the year May 2004 - April 2009 were retrospectively reviewed. The data included age, sex, month and time of incident, site of bite, dose of anti--snake venom, time of anti--snake venom, administration, duration of mechanical ventilation, complications and death of a victim.
Pearson's correlation test, paired samples t-test.
113 patients reported to the Accident and Emergency with history of snake bite. 26 patients were referred to other hospital, 17 patients were brought dead, and 70 patients were admitted to the intensive care unit. In 59 snake-bite victims, maximum data could be recovered. Krait was the most common type of snake bite reported. There was a male preponderance (69.4%) with age ranging between 20 and 40 years (52.5%). The mean lag time (time elapsed between bite and first dose of anti--snake venom) was 5.3 ± 1.4 h and the mean anti-snake venom dose was 12.3 ± 2.4 vials. There was a positive and significant correlation between lag time and total dose of anti--snake venom (correlation coefficient =0.956, P<0.0001). Overall 72.9% patients required mechanical ventilation with a mean duration of 56.2 ± 16.1 h. 10.2% patients sustained cardiac arrest, 8.7% patients developed ventilator associated pneumonia, 6.7% suffered mild anti-snake venom reaction, 6.7% had hypotension and 5.1% patients developed renal failure. The overall mortality was 5.1%.
在热带国家，蛇咬伤是发病和死亡的常见原因。
分析蛇咬伤受害者的治疗结果。
对麻醉科重症监护病房的数据进行回顾性分析。
对2004年5月至2009年4月期间入住重症监护病房接受蛇咬伤治疗的所有患者进行回顾性研究。数据包括年龄、性别、事件发生的月份和时间、咬伤部位、抗蛇毒血清剂量、抗蛇毒血清给药时间、机械通气时间、并发症和受害者死亡情况。
皮尔逊相关检验、配对样本t检验。
113例有蛇咬伤史的患者到急诊就诊。26例患者被转至其他医院，17例患者送来时已死亡，70例患者入住重症监护病房。在59例蛇咬伤受害者中，大部分数据可以获取。报道的最常见蛇咬伤类型是金环蛇。男性居多（69.4%），年龄在20至40岁之间（52.5%）。平均延迟时间（咬伤至首剂抗蛇毒血清的时间间隔）为5.3±1.4小时，平均抗蛇毒血清剂量为12.3±2.4瓶。延迟时间与抗蛇毒血清总剂量之间存在正相关且具有显著性（相关系数=0.956，P<0.0001）。总体而言，72.9%的患者需要机械通气，平均时间为56.2±16.1小时。10.2%的患者发生心脏骤停，8.7%的患者发生呼吸机相关性肺炎，6.7%的患者出现轻度抗蛇毒血清反应，6.7%的患者出现低血压，5.1%的患者发生肾衰竭。总体死亡率为5.1%。
