Yang Yaling, Chan Sze Wa, Hu Miao, Walden Richard, Tomlinson Brian
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong.
ISRN Cardiol. 2011;2011:397136. doi: 10.5402/2011/397136. Epub 2011 Jun 16.
Cardiovascular diseases are the major cause of morbidity and mortality worldwide, and there is considerable interest in the role of dietary constituents and supplements in the prevention and treatment of these disorders. We reviewed the major publications related to potential effects on cardiovascular risk factors and outcomes of some common dietary constituents: carotenoids, flavonoid-rich cocoa, tea, red wine and grapes, coffee, omega-3 fatty acids, and garlic. Increased intake of some of these has been associated with reduced all-cause mortality or reduced incidence of myocardial infraction, stroke, and hypertension. However, although the evidence from observational studies is supportive of beneficial effects for most of these foodstuffs taken as part of the diet, potential benefits from the use of supplements derived from these natural products remain largely inconclusive.
心血管疾病是全球发病和死亡的主要原因，人们对饮食成分和补充剂在这些疾病的预防和治疗中的作用非常感兴趣。我们回顾了一些常见饮食成分对心血管危险因素和结局的潜在影响的主要出版物：类胡萝卜素、富含黄酮类化合物的可可、茶、红酒和葡萄、咖啡、ω-3脂肪酸和大蒜。增加其中一些成分的摄入量与全因死亡率降低或心肌梗死、中风和高血压发病率降低有关。然而，尽管观察性研究的证据支持将这些食物中的大多数作为饮食的一部分具有有益效果，但从这些天然产物衍生的补充剂的潜在益处仍 largely inconclusive（很大程度上尚无定论）。 （注：inconclusive 原词为英文，可根据实际情况考虑是否保留英文或进一步解释，这里按要求保留英文）
